Results 51 to 60 of about 426,181 (263)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Land, 2020 This paper presents the results of 39 years of observations conducted at the Chabyda station to monitor the thermal state of permafrost landscapes under current climatic warming.
Stepan P Varlamov +2 more
doaj +1 more source
Ground Temperature Variability in Poznań (2011–2020)
Quaestiones Geographicae, 2022 The manuscript concerns the analysis of the ground temperature in Poznań in the years 2011–2020. Data generally available on the Institute of Meteorology and Water Management – National Research Institute (IMGW-PIB) website were used.
Szyga-Pluta Katarzyna
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
FEBS Letters, EarlyView.This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
EnergiesThis article presents an original, multi-depth soil-temperature monitoring system based on TMP117 digital sensors designed for deployment at several depths.
Ewa Daniszewska +3 more
doaj +1 more source
Environmental Research Letters, 2020 Seasonally frozen ground (SFG) is a critical component of the Earth’s surface that affects energy exchange and the water cycle in cold regions. The estimation of SFG depth has generally required intensive parameterization which has limited estimates in ...
Fang Ji +4 more
doaj +1 more source
Clustering of Handheld Thermal Camera Images in Volcanic Areas and Temperature Statistics
Remote Sensing, 2022 Thermal camera use is becoming ever more widespread in volcanic and environmental research and monitoring activities. Depending on the scope of an investigation and on the type of thermal camera used, different software for thermal infrared (IR) images ...
Francesca Cirillo +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
GeosciencesThis research presents a comprehensive environmental assessment of a small mountain permafrost catchment of the Anmangynda River in the Upper Kolyma Highland (Northeastern Asia) over the period of 2021–2023.
Olga Makarieva +4 more
doaj +1 more source