Results 61 to 70 of about 426,181 (263)

Permafrost-Landscape Map of the Republic of Sakha (Yakutia) on a Scale 1:1,500,000

Geosciences, 2018
The history of permafrost landscape map compilation is related to the study of ecological problems with permafrost. Permafrost-landscape studies are now widely used in geocryological mapping. Permafrost-landscape classifications and mapping are necessary
Alexander N. Fedorov, Nikolay F. Vasilyev, Yaroslav I. Torgovkin, Alena A. Shestakova, Stepan P. Varlamov, Mikhail N. Zheleznyak, Viktor V. Shepelev, Pavel Y. Konstantinov, Svetlana S. Kalinicheva, Nikolay I. Basharin, Viktor S. Makarov, Innokenty S. Ugarov, Peter V. Efremov, Radomir N. Argunov, Larisa S. Egorova, Vera V. Samsonova, Andrey G. Shepelev, Alexander I. Vasiliev, Rosaliya N. Ivanova, Alexey A. Galanin, Vasily M. Lytkin, Georgy P. Kuzmin, Viktor V. Kunitsky   +22 more
doaj   +1 more source

Monitoring the Permafrost Conditions along Pipeline Routes in Central Yakutia, Russia

Land, 2022
Pipelines are critical infrastructure for Yakutia, transporting vital supplies to communities in this vast northern region. The pipeline routes in central Yakutia traverse areas of ice-rich permafrost that is sensitive to temperature changes.
Stepan Varlamov, Pavel Skryabin, Aleksandr Zhirkov, Zhi Wen   +3 more
doaj   +1 more source

Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila

FEBS Letters, EarlyView.
Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia, Anna Dósa, Asha Kiran Maddali, András Jipa, Hajnalka Laczkó‐Dobos, Péter Lőw, Gábor Juhász   +6 more
wiley   +1 more source

Online Temperature Modeling in the Hangzone Sonnenberg, Zurich

Engineering Proceedings
Continuous measurements within the water distribution network of the Water Supply Zurich (WVZ) revealed surprisingly high water temperatures in different locations, especially during the summer months.
Fabio Belotti, Harald Tarnowski, Zdenek Svitak, Petr Ingeduld   +3 more
doaj   +1 more source

Thermal Regime and Variations in the Island Permafrost Near the Northern Permafrost Boundary in Xidatan, Qinghai–Tibet Plateau

Frontiers in Earth Science, 2021
Although the thermal regime and degradation of permafrost on the Qinghai-Tibet Plateau (QTP) have been widely documented, little information exists regarding the island permafrost in the area. Ground temperatures were therefore measured for 8 years (2013–
Guoan Yin, Jing Luo, Fujun Niu, Zhanju Lin, Minghao Liu   +4 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Undisturbed ground temperature in Melbourne [PDF]

AIP Conference Proceedings, 2019
The ground surface temperature changes with the diurnal cycle of solar radiation and ambient air temperature. However, the amplitude of the ground temperature variation diminishes with the increase of the depth of the ground and after a certain depth of the ground, it becomes almost constant, where is termed “undisturbed ground temperature (UGT)”.
Sheikh Khaleduzzaman Shah, Lu Aye, Behzad Rismanchi   +2 more
openaire   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

INFLUENCE OF SURFACE CONDITIONS ON GROUND TEMPERATURE

Canadian Journal of Earth Sciences, 1967
Ground temperatures were measured under two parking lots, one of which was cleared of snow in winter, and monthly and annual average surface temperatures were estimated by extrapolation. The surface temperatures were compared with monthly and annual surface and air temperatures measured at a nearby grassed site.
openaire   +3 more sources

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source