Results 61 to 70 of about 2,571,636 (343)
Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren +16 more
wiley +1 more source
Modified zeolites in ground water treatment [PDF]
, 2015 There are presented results of technological experiments carried out in Water Treatment Plant Kúty. The goal of this study was to compare modified zeolite known as clinoptilolite (rich deposits of clinoptilolite were found in the region of East Slovakia ...
Barloková, Danka +2 more
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All the Water in the World [PDF]
This activity will help students to recognize that there is a lot of water in the world, but that not very much of it can be used for our drinking water and other water supply needs. They will see that ground water is a very small percentage of the Earth'
core +4 more sources
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
The artesian water of the Ruskin area of Hillsborough County, Florida: interim report [PDF]
, 1953 The purpose of the investigation is to make a detailed study of the geology and ground water in the Ruskin area, especially as related to the problem of salt-water encroachment.
Peek, Harry M.
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Discover WaterThis study assessed the extent of potential toxic element (PTE) contamination and its associated health risks in groundwater from the Tista Floodplain, Rangpur, northern Bangladesh.
Mir Md Tasnim Alam +6 more
doaj +1 more source
Molecular Oncology, EarlyView.In luminal (ER+) breast carcinoma (BC), miRNA profiling identified miR‐195‐5p as a key regulator of proliferation that targets CHEK1, CDC25A, and CCNE1. High CHEK1 expression correlates with worse relapse‐free survival after chemotherapy, especially in patients with luminal A subtype.
Veronika Boušková +14 more
wiley +1 more source
Journal of Agricultural Meteorology, 1953 1. The annual course of the ground-water in the field of Kyoushu Agr. Exp. Ssation is shown in Fag. 2; and the measuring apparatus in Fig. 1.2. The ground-water level is deeper than 1.5m in winter or spring season (non-irrigating term), and shallower than 1.0m in summer or autumn season (irrigating term for the paddy field).
S. Sato, Y. Funahashi
openaire +3 more sources
Understanding and measuring mechanical signals in the tumor stroma
FEBS Open Bio, EarlyView.This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz +3 more
wiley +1 more source
Identification of Optimal Locations for Sampling Ground Water for Pesticides in the Mississippi Delta Region of Eastern Arkansas [PDF]
, 1996 Concerns about the presence of pesticides in the Mississippi River Valley alluvial aquifer in the Arkansas Delta have generated the need to develop a map of ground water vulnerability for this region comprised of approximately 10 million acres.
Lin, H. S. +2 more
core +2 more sources