Results 21 to 30 of about 436,301 (266)

Rhamnose polysaccharide-decorated outer membrane vesicles as a vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Vaccine: X
Group A Streptococcus (Strep A) cause a wide range of human-exclusive infections, annually killing more than 500,000 people. Antibiotic resistance incidence of invasive Strep A tripled in the past decade and emphasises the need to develop a universal ...
Sowmya Ajay Castro, Sarah Thomson, Helen Alexandra Shaw, Azul Zorzoli, Benjamin H. Meyer, Mark Reglinski, Mark McNeil, Helge C. Dorfmueller   +7 more
doaj   +1 more source

Efficacy of Alum-Adjuvanted Peptide and Carbohydrate Conjugate Vaccine Candidates against Group A Streptococcus Pharyngeal Infection in a Non-Human Primate Model

Vaccines
Vaccine development against group A Streptococcus (GAS) has gained traction in the last decade, fuelled by recognition of the significant worldwide burden of the disease.
Tania Rivera-Hernandez, Diane G. Carnathan, Johanna Richter, Patrick Marchant, Amanda J. Cork, Gayathiri Elangovan, Anna Henningham, Jason N. Cole, Biswa Choudhury, Peter M. Moyle, Istvan Toth, Michael R. Batzloff, Michael F. Good, Paresh Agarwal, Neeraj Kapoor, Victor Nizet, Guido Silvestri, Mark J. Walker   +17 more
doaj   +1 more source

Preoperative Oral Carbohydrate Levels in Patients with Type 2 Diabetes Mellitus: The Clinical Guiding Significance of Free Fatty Acids

Frontiers in Surgery, 2022
BackgroundIt is still controversial whether preoperative oral carbohydrate (POC) should be applied to patients with type 2 diabetes mellitus (T2DM) in the enhanced recovery after surgery (ERAS) protocol.
Jiuhui Yang, Jiuhui Yang, Jiuhui Yang, Xiangming Ding, Xiangming Ding, Xiangming Ding, Ning Wang, Ning Wang, Ning Wang, Yujin Pan, Yujin Pan, Yujin Pan, Erwei Xiao, Erwei Xiao, Erwei Xiao, Senmao Mu, Senmao Mu, Senmao Mu, Liancai Wang, Liancai Wang, Liancai Wang, Dongxiao Li, Dongxiao Li, Dongxiao Li, Deyu Li, Deyu Li, Deyu Li   +26 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

GASTRIC RESIDUAL VOLUME BY MAGNETIC RESSONANCE AFTER INTAKE OF MALTODEXTRIN AND GLUTAMINE: a randomized double-blind, crossover study

Arquivos de Gastroenterologia
ContextThe addition of glutamine in preoperative drinks may enhance the benefits of carbohydrate alone.ObjectivesTo evaluate the gastric residual volume after the intake of a beverage containing carbohydrate plus glutamine.MethodsEleven healthy ...
Luigi R BRIANEZ, Cervantes CAPOROSSI, Yure W de MOURA, Lorena A DIAS, Regis V LEAL, José E de AGUILAR-NASCIMENTO   +5 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Metabolic consequences of perioperative oral carbohydrates in breast cancer patients — an explorative study

BMC Cancer, 2019
Background The metabolic consequences of preoperative carbohydrate load in breast cancer patients are not known. The present explorative study investigated the systemic and tumor metabolic changes after preoperative per-oral carbohydrate load and their ...
Tone Hoel Lende, Marie Austdal, Tone Frost Bathen, Anne Elin Varhaugvik, Ivar Skaland, Einar Gudlaugsson, Nina G. Egeland, Siri Lunde, Lars A. Akslen, Kristin Jonsdottir, Emiel A. M. Janssen, Håvard Søiland, Jan P. A. Baak   +12 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Adaptation of Chinese perch (Siniperca chuatsi) to different levels of dietary carbohydrates

Aquaculture Reports
The objective of the study was to investigate the effects of dietary carbohydrate on growth performance, feed utilization, proximate compositions, and hepatic glucolipid metabolism in Chinese perch.
Qiwei Zhang, Xu-Fang Liang, Yanpeng Zhang, Hexiong Feng   +3 more
doaj   +1 more source

The modulation of carbohydrate intake and intermittent fasting in obese Saudi women: a pilot study

Bulletin of the National Research Centre, 2023
Background In recent years, the prevalence of overweight and obesity has increased, leading to the development of various dietary interventions as potential treatments.
Muneerah H. Al-jammaz, Abdulrahman Al-kalifah, Nawal Abdullah Al-bader, Maha H. Al-hussain   +3 more
doaj   +1 more source