Results 111 to 120 of about 115,722,656 (247)

Epidemiology of Streptococcus pyogenes Disease before, during, and after COVID-19 Pandemic, Germany, 2005–2023

open access: yesEmerging Infectious Diseases
We analyzed 3,081 invasive and noninvasive Streptococcus pyogenes cases (January 2005–December 2023) at a tertiary care hospital in southwest Germany. Absolute numbers of case-patients increased each year from 2005 until the COVID-19 pandemic.
Irene Burckhardt, Florian Burckhardt
doaj   +1 more source

Emergent Invasive Group A Streptococcus dysgalactiae subsp. equisimilis, United States, 2015–2018

open access: yesEmerging Infectious Diseases, 2019
The term group A Streptococcus is considered synonymous for the species Streptococcus pyogenes. We describe an emergent invasive S. dysgalactiae subspecies equisimilis lineage that obtained the group A antigen through a single ancestral recombination ...
Sopio Chochua   +9 more
doaj   +1 more source

Engineered Transformer Base Editor with Enhanced Editing Efficiency

open access: yesAdvanced Science, EarlyView.
A highly efficient transformer base editor system achieves robust genomic editing in a humanized mouse model. This work establishes a versatile and translatable platform, opening new avenues for precision gene therapy. ABSTRACT Canonical cytosine base editors (CBEs) achieve precise C‐to‐T conversions without inducing DNA double‐strand breaks (DSBs ...
Bowen Chen   +5 more
wiley   +1 more source

Group G streptococci of human origin

open access: yes, 2016
Bakalářská práce se zabývá výhradně charakteristikou streptokoků se skupinovým antigenem G. Hlavním tématem jsou onemocnění, která jsou způsobena streptokoky se skupinovým antigenem G (hlavně Streptococcus dysgalactiae subsp. equisimilis). Dalším tématem
Čápová, Aneta
core   +1 more source

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

open access: yesAdvanced Science, EarlyView.
Concurrent YAP hyperactivation and Tp53 loss in Atp4b‐expressed parietal cell lineage drives gastric cancer initiation, multi‐organ metastasis, and intrinsic resistance to anti‐PD‐1 therapy. BST2 emerges as a direct YAP‐TEAD transcriptional target that engages PIRA2 on myeloid cells to establish an immunosuppressive microenvironment.
Weihong Zhang   +17 more
wiley   +1 more source

Fermentation Potentials of Baobab Pulp Extract in Soy Yoghurt Production

open access: yesAgriFood: Journal of Agricultural Products for Food, EarlyView.
The research work was about the importance of sourcing for alternative inoculants to replace the main inoculants regularly used for yoghurt production. The search for baobab pulp extract as replacement yielded result, as soy yoghurt was successfully produced.
Adegbola Oladele Dauda   +6 more
wiley   +1 more source

Effects of a Chlorhexidine Varnish on the Mutans Streptococci and on Dental Caries [PDF]

open access: yes, 1997
The purpose of this study was to determine the effects of a chlorhexidine varnish-sealant on the mutans streptococci and on caries outcome variables, in 113 female school-children 10 to 15 years-old, in Rio de Janeiro, Brazil.
C. Djahjah   +5 more
core  

Microbial‐Metabolite Signatures Are Associated With Glucocorticoid Responsiveness in Chronic Rhinosinusitis With Nasal Polyps

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang   +7 more
wiley   +1 more source

Group A Streptococcus among American Indian Persons, White Mountain Apache Tribal Lands, United States, 2016–2019

open access: yesEmerging Infectious Diseases
American Indian populations have higher rates of invasive disease because of group A Streptococcus (GAS). This study describes the rates of severe and invasive GAS (siGAS) infections and the distribution of circulating emm types among nonsevere and ...
Catherine G. Sutcliffe   +8 more
doaj   +1 more source

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

open access: yesAdvanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi   +6 more
wiley   +1 more source

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