Results 81 to 90 of about 115,722,656 (247)

Inflammation Unchecked: Concurrent Kawasaki Disease and Stevens‐Johnson Syndrome in an 18‐Month‐Old Child

Arthritis Care &Research, EarlyView.
Catherine Deffendall, Jodi Backalar, Elizabeth Acevedo Zapata, Adriana Della Porta, Lorin Bibb, Tyler Reese, Charlotte M. Brown   +6 more
wiley   +1 more source

Integrated Single‐Nucleus Multi‐Omics Atlases Reveal Lineage Plasticity and Regulatory Networks of Luminal Epithelial Cells During Mammary Gland Lactation and Involution

Advanced Science, EarlyView.
This study integrates single‐cell multi‐omics, spatial transcriptomics, and cross‐species comparative analyses to systematically characterize the cellular composition and differentiation trajectories of goat mammary epithelial cells, along with the gene regulatory networks and intercellular communication mechanisms governing these trajectories, thereby
Xiaoru Yan, Xiaoyu Mi, Guanghui Tan, Xinmei Li, Zhenliang Zhu, Zhenyu Wei, Huimei Fan, Yamei Wu, Tao Shi, Lingzhao Fang, Yuanpeng Gao, Yu Wang, Jun Liu   +12 more
wiley   +1 more source

SURVEY OF CARRIER RATE OF GROUP A HEMOLYTIC STREPTOCOCCI

Iranian Journal of Public Health, 1972
This study was undertaken in order to ascertain the carrier rate of group A hemolytic streptococci in the throats of pupils in selected schools of Tehran, and to evaluate the role of socio-economical factors on carrier state.
M. Nadimi, T. Zirak Zadeh   +1 more
doaj  

Prospective surveillance of invasive group a streptococcal disease, Fiji, 2005-2007. [PDF]

, 2009
We undertook a prospective active surveillance study of invasive group A streptococcal (GAS) disease in Fiji over a 23-month period, 2005-2007. We identified 64 cases of invasive GAS disease, which represents an average annualized all-ages incidence of 9.
Adam Jenney, E. Kim Mullholland, Batzloff, M, Steer, AC, Jonathan R. Carapetis, Kado, Joseph, Carapetis, JR, Good, Michael F, Carapetis, Jonathan R., Waqatakirewa, L, Jenney, A, Mullholland, E Kim, Jenney, Adam, Kado, J, Steer, Andrew C., Carapetis, Jonathan R, Andrew C. Steer, Good, Michael F., Lepani Waqatakirewa, Good, MF, Waqatakirewa, Lepani, Steer, Andrew C, Joseph Kado, Michael Batzloff, Michael F. Good, Mullholland, EK, Batzloff, Michael, Kim Mullholland, E.   +27 more
core   +1 more source

The Natural Product Corramycin Acts as a DNA Gyrase Poison and Overcomes Fluoroquinolone Resistance in Mycobacterium tuberculosis

Advanced Science, EarlyView.
Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries, Jennifer Herrmann, Michael Dal Molin, Yaëlle Wormser, Timo Risch, Yunsheng Gao, Gareth Prosser, Francesca Gubellini, Ariel Mechaly, Joshua B. Wallach, Anthony Castro, Arka Banerjee, Sari Rasheed, Alexander Horn, Mathias Müsken, Michael Kurz, Lindsay Sonnenkalb, Viola Dreyer, Stefan Niemann, Sönke Andres, Dirk Schnappinger, Uli Kazmaier, Norbert Reiling, Rolf Müller, Jan Rybniker, Stéphanie Petrella   +25 more
wiley   +1 more source

Changing trends in Streptococcus pyogenes bacteraemia in adults in the post-COVID era

BMC Infectious Diseases
Background Since 2022, an increasing number of invasive group A streptococcal (iGAS) infections have been reported, with increasing severity and lethality.
Olga Džupová, Hynek Bartoš, Blanka Sýkorová, Jiří Beneš   +3 more
doaj   +1 more source

Gut‐Liver Translocation of Bacteroides Uniformis Alleviates Advanced Metabolic Dysfunction‐Associated Steatotic Liver Disease by Suppressing Hepatocyte Ferroptosis via Propionic Acid Secretion

Advanced Science, EarlyView.
Systematic characterization of the liver‐resident microbiota in advanced metabolic dysfunction‐associated steatotic liver disease (MASLD) reveals a consistent depletion of Bacteroides uniformis (B. uniformis) in both hepatic and gut microbial communities. Oral gavage of B.
Haiyang Liu, Zun Fan, Zhen Liu, Lei Qin, Xin Zhao   +4 more
wiley   +1 more source

Antimicrobial and anti-virulence activity of capsaicin against erythromycin-resistant, cell-invasive Group A streptococci

Frontiers in Microbiology, 2015
Capsaicin (8-methyl-N-vanillyl-6-nonenamide) is the active component of Capsicum plants (chilli peppers), which are grown as food and for medicinal purposes since ancient times, and is responsible for the pungency of their fruit.
Emanuela eMarini, Gloria eMagi, Marina eMingoia, Armanda ePugnaloni, Bruna eFacinelli   +4 more
doaj   +1 more source

Rapid antibody capture assay for detection of group-A streptococci using monoclonal antibody and colloidal gold-monospecific polyvalent antibody conjugate

, 1992
A rapid one step, sensitive and specific antibody capture assay for detection of group-A streptococci from the throat swabs of children is described. Monoclonal antibody either MA-106 or MA-107 specific for group-A streptococci polysaccharide (APS) was ...
Gupta, S. K., Gupta, Rita, Talwar, G. P.
core   +1 more source

Artificial Intelligence‐Guided Phenotypic Drug Repurposing Against Streptococcus pneumoniae

Advanced Science, EarlyView.
Integrated artificial intelligence (AI) ensembles identify highly potent repurposed drugs against Streptococcus pneumoniae. Prospective virtual screening of 6747 drugs uncovers nine active candidates, including thiostrepton. This drug exhibits low picomolar potency and bypasses established resistance in multidrug‐resistant strains, demonstrating an ...
Joshua S. Fitch, Muhammad D. Ariadi, Min Jung Kwun, Leonie Howells, Saiveth Hernandez‐Hernandez, Nicholas J. Croucher, Pedro J. Ballester   +6 more
wiley   +1 more source