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Quorum sensing in group A Streptococcus [PDF]
Quorum sensing (QS) is a widespread phenomenon in the microbial world that has important implications in the coordination of population-wide responses in several bacterial pathogens. In Group A Streptococcus (GAS), many questions surrounding QS systems remain to be solved pertaining to their function and their contribution to the GAS lifestyle in the ...
Jimenez, Juan Cristobal +1 more
openaire +3 more sources
Correlates of Protection for M Protein-Based Vaccines against Group A Streptococcus
Group A streptococcus (GAS) is known to cause a broad spectrum of illness, from pharyngitis and impetigo, to autoimmune sequelae such as rheumatic heart disease, and invasive diseases.
Shu Ki Tsoi +4 more
doaj +1 more source
GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus
Group A Streptococcus (GAS) causes about 500,000 annual deaths globally, and no vaccines are currently available. The Group A Carbohydrate (GAC), conserved across all GAS serotypes, conjugated to an appropriate carrier protein, represents a promising ...
Elena Palmieri +14 more
doaj +1 more source
Streptococcus pyogenes and re-emergence of scarlet fever as a public health problem
Explosive outbreaks of infectious diseases occasionally occur without immediately obvious epidemiological or microbiological explanations. Plague, cholera and Streptococcus pyogenes infection are some of the epidemic-prone bacterial infections.
Samson SY Wong, Kwok-Yung Yuen
doaj +1 more source
Group A Streptococcus (GAS) or Streptococcus pyogenes, affects an estimated 800 million people each year. Most of the resulting estimated 639,000 annual deaths are related to rheumatic heart disease (RHD) and its complications. Resource-limited areas account for the vast majority of cases, although outbreaks still occur in industrialized countries. GAS
Hand, Robert M. +2 more
openaire +2 more sources
The risk for invasive streptococcal infection has not been clearly quantified among persons experiencing homelessness (PEH). We compared the incidence of detected cases of invasive group A Streptococcus infection, group B Streptococcus infection, and ...
Emily Mosites +9 more
doaj +1 more source
Effects of Streptococcal Pyrogenic Exotoxin B on Pathogenesis of Streptococcus pyogenes
Streptococcus pyogenes (group A streptococcus, GAS) is a ubiquitous and important human bacterial pathogen. This organism possesses several virulence factors to establish infection.
Chuan Chiang-Ni, Jiunn-Jong Wu
doaj +1 more source
Background Beta-hemolytic streptococci carrier rates in children living in low-income countries are high ranging from 10 to 50%. Although most of these children are asymptomatic, they are a reservoir and pose a risk of transmission. The aim of this study
Irene Nayiga +3 more
doaj +1 more source
Evaluation of a Streptococcal Pharyngitis Score in Southern Taiwan
Group A streptococcus (GAS) pharyngitis can cause serious complications such as rheumatic heart disease. The McIsaac sore throat score is a clinical prediction score used to improve the detection rate of GAS pharyngitis.
Ching-Tang Shih +2 more
doaj +1 more source
The clinical development of group A streptococcal (GAS) vaccines will require the implementation of a standardized, high-throughput assay to measure the activity of functional opsonic antibodies in vaccine recipients. In the present study, we adapted and
Sanaz Salehi +3 more
doaj +1 more source

