Protocol for Proteome Analysis of Group A Streptococcus
This chapter describes a protocol for the separation of different cell fractions from Streptococcus pyogenes and sample preparation for analysis by mass spectrometry. The presented approach can be used for the analysis of all subcellular proteomes from S.
Wilk, Laura,, Lund University.
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Background: Group A streptococcus (GAS) is the most common cause of bacterial pharyngitis. This study aimed to characterize the molecular epidemiology of GAS infection using an emmtyping and emm-clustering approach.
Seon A Jo, Seungjun Lee, Sunjoo Kim
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It was gratifying to read that the authors of this commentary[1][1] on group A streptococcus mention the significant rate of colonization versus infection. Surprisingly, this was not mentioned in the related research article.[2][2] This continuing uncertainty, so appropriate in science ...
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Emergence of a new highly successful acapsular Group A Streptococcus clade of the genotype emm89 in the United Kingdom [PDF]
This work was supported by the National Institute for Health Research Biomedical Research Centre awarded to Imperial College Healthcare Trust, and the UK Clinical Research Collaboration (National Centre for Infection Prevention & Management).Group A ...
Abbott, James +38 more
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Quorum sensing in group A Streptococcus [PDF]
Quorum sensing (QS) is a widespread phenomenon in the microbial world that has important implications in the coordination of population-wide responses in several bacterial pathogens. In Group A Streptococcus (GAS), many questions surrounding QS systems remain to be solved pertaining to their function and their contribution to the GAS lifestyle in the ...
Jimenez, Juan Cristobal +1 more
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Correlates of Protection for M Protein-Based Vaccines against Group A Streptococcus
Group A streptococcus (GAS) is known to cause a broad spectrum of illness, from pharyngitis and impetigo, to autoimmune sequelae such as rheumatic heart disease, and invasive diseases.
Shu Ki Tsoi +4 more
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A Mouse Nasopharyngeal Colonization Model for Group A Streptococcus
Group A Streptococcus (GAS) often exists as an asymptomatic colonizer of the upper respiratory tract in humans. Unsurprisingly, a high proportion of symptomatic infections caused by GAS include pharyngitis.
Jacelyn M. S. Loh +5 more
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Genomic evidence for the evolution of Streptococcus equi : host restriction, increased virulence, and genetic exchange with human pathogens [PDF]
The continued evolution of bacterial pathogens has major implications for both human and animal disease, but the exchange of genetic material between host-restricted pathogens is rarely considered. Streptococcus equi subspecies equi (S.
Parkhill Julian +117 more
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Genetic islands of Streptococcus agalactiae strains NEM316 and 2603VR and their presence in other Group B Streptococcal strains [PDF]
BACKGROUND: Streptococcus agalactiae (Group B Streptococcus; GBS) is a major contributor to obstetric and neonatal bacterial sepsis. Serotype III strains cause the majority of late-onset sepsis and meningitis in babies, and thus appear to have an ...
Jones, N +20 more
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Evidence for niche adaptation in the genome of the bovine pathogen Streptococcus uberis [PDF]
Background Streptococcus uberis, a Gram positive bacterial pathogen responsible for a significant proportion of bovine mastitis in commercial dairy herds, colonises multiple body sites of the cow including the gut, genital tract and mammary gland ...
Andy Barron +57 more
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