Results 21 to 30 of about 1,880,201 (344)

GMMA as an Alternative Carrier for a Glycoconjugate Vaccine against Group A Streptococcus

Vaccines, 2022
Group A Streptococcus (GAS) causes about 500,000 annual deaths globally, and no vaccines are currently available. The Group A Carbohydrate (GAC), conserved across all GAS serotypes, conjugated to an appropriate carrier protein, represents a promising ...
Elena Palmieri, Zoltán Kis, James Ozanne, Roberta Di Benedetto, Beatrice Ricchetti, Luisa Massai, Martina Carducci, Davide Oldrini, Gianmarco Gasperini, Maria Grazia Aruta, Omar Rossi, Cleo Kontoravdi, Nilay Shah, Fatme Mawas, Francesca Micoli   +14 more
doaj   +1 more source

State-of-the-art of invasive Group A Streptococcus infection in children: protocol for a scoping review of the literature with a focus on predictors of invasive infection [version 1; peer review: 2 approved]

F1000Research, 2023
Background: Invasive group A streptococcus infection (iGAS) is a serious, sometimes life-threatening condition, with high case fatality rates and high morbidity whose incidence is greatly increased in the last years. Despite the increasing importance and
Piero Valentini, Danilo Buonsenso, Carolina Gentili, Valentina Pulcinelli, Francesco Mariani, Laura Martino   +5 more
doaj  

The Path to Group A Streptococcus Vaccines: World Health Organization Research and Development Technology Roadmap and Preferred Product Characteristics

Clinical Infectious Diseases, 2019
Group A Streptococcus (GAS) infections result in a considerable underappreciated burden of acute and chronic disease globally. A 2018 World Health Assembly resolution calls for better control and prevention.
J. Vekemans, Fernando A. Gouvea-Reis, Jerome H. Kim, J. Excler, P. Smeesters, K. O'Brien, C. V. Van Beneden, A. Steer, J. Carapetis, D. Kaslow   +9 more
semanticscholar   +1 more source

THE PNEUMONIAS: STREPTOCOCCUS AND PNEUMOCOCCUS GROUPS [PDF]

JAMA: The Journal of the American Medical Association, 1918
A conference of medical officers from Fort Sam Houston and Camp Travis was held, Jan. 3, 1918, for the purpose of considering the pneumonia situation. Various points in the determination of the causative organism in pneumonia following measles were considered, methods of procedure were suggested, and the laboratory force was organized to take up the ...
James G. Cumming, Charles F. Lynch, Charles B. Spruit   +2 more
openaire   +3 more sources

Risk for Invasive Streptococcal Infections among Adults Experiencing Homelessness, Anchorage, Alaska, USA, 2002–2015

Emerging Infectious Diseases, 2019
The risk for invasive streptococcal infection has not been clearly quantified among persons experiencing homelessness (PEH). We compared the incidence of detected cases of invasive group A Streptococcus infection, group B Streptococcus infection, and ...
Emily Mosites, Tammy Zulz, Dana Bruden, Leisha Nolen, Anna Frick, Louisa Castrodale, Joseph McLaughlin, Chris Van Beneden, Thomas W. Hennessy, Michael G. Bruce   +9 more
doaj   +1 more source

Increase in invasive group A streptococcal infections and emergence of novel, rapidly expanding sub-lineage of the virulent Streptococcus pyogenes M1 clone, Denmark, 2023

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 2023
A highly virulent sub-lineage of the Streptococcus pyogenes M1 clone has been rapidly expanding throughout Denmark since late 2022 and now accounts for 30% of the new invasive group A streptococcal infections.
T. Johannesen, Charlotte Munkstrup, S. Edslev, Sharmin Baig, Stine Nielsen, T. Funk, Dennis Karsten Kristensen, Lars Hervig Jacobsen, Signe Fischer Ravn, Niels Bindslev, S. Gubbels, M. Voldstedlund, P. Jokelainen, Søren Hallstrøm, A. Rasmussen, K. Kristinsson, David Fuglsang-Damgaard, R. Dessau, Agnieszka Barbara Olsén, C. Jensen, Annette Skovby, S. Ellermann-Eriksen, T. G. Jensen, E. Dzajic, C. Østergaard, Steen Lomborg Andersen, S. Hoffmann, P. Andersen, M. Stegger   +28 more
semanticscholar   +1 more source

Streptococcus pyogenes and re-emergence of scarlet fever as a public health problem

Emerging Microbes and Infections, 2012
Explosive outbreaks of infectious diseases occasionally occur without immediately obvious epidemiological or microbiological explanations. Plague, cholera and Streptococcus pyogenes infection are some of the epidemic-prone bacterial infections.
Samson SY Wong, Kwok-Yung Yuen
doaj   +1 more source

Effects of Streptococcal Pyrogenic Exotoxin B on Pathogenesis of Streptococcus pyogenes

Journal of the Formosan Medical Association, 2008
Streptococcus pyogenes (group A streptococcus, GAS) is a ubiquitous and important human bacterial pathogen. This organism possesses several virulence factors to establish infection.
Chuan Chiang-Ni, Jiunn-Jong Wu
doaj   +1 more source

Group A Streptococcus pharyngitis and pharyngeal carriage: A meta-analysis

PLoS Neglected Tropical Diseases, 2018
Objective Antibiotic treatment of Group A Streptococcus (GAS) pharyngitis is important in acute rheumatic fever (ARF) prevention, however clinical guidelines for prescription vary.
J. Oliver, Erandi Malliya Wadu, N. Pierse, N. Moreland, D. Williamson, M. Baker   +5 more
semanticscholar   +1 more source

VEGF-Mediated Augmentation of Autophagic and Lysosomal Activity in Endothelial Cells Defends against Intracellular Streptococcus pyogenes

mBio, 2022
Group A Streptococcus (GAS), a deleterious human-pathogenic bacterium, causes life-threatening diseases such as sepsis and necrotic fasciitis. We recently reported that GAS survives and replicates within blood vessel endothelial cells because these cells
Shiou-Ling Lu, Hiroko Omori, Yi Zhou, Yee-Shin Lin, Ching-Chuan Liu, Jiunn-Jong Wu, Takeshi Noda   +6 more
doaj   +1 more source