Results 21 to 30 of about 258,861 (311)

Prevalence of group a streptococcus pharyngeal carriage and clinical manifestations in school children aged 5–15 yrs in Wakiso District, Uganda

open access: yesBMC Infectious Diseases, 2017
Background Beta-hemolytic streptococci carrier rates in children living in low-income countries are high ranging from 10 to 50%. Although most of these children are asymptomatic, they are a reservoir and pose a risk of transmission. The aim of this study
Irene Nayiga   +3 more
doaj   +1 more source

Successful anesthesia case of emergency cesarean section complicated with pregnancy-related group: A streptococcus sepsis

open access: yesJournal of Obstetric Anaesthesia and Critical Care, 2022
Pregnancy-related Group A streptococcus (GAS) sepsis is a rare, rapidly progressing life-threatening disease. Previous reports described the clinical features of pregnancy-related GAS sepsis, however, the evidence regarding general anesthesia is ...
Yuta Kawatsu   +2 more
doaj   +1 more source

Evaluation of a Streptococcal Pharyngitis Score in Southern Taiwan

open access: yesPediatrics and Neonatology, 2012
Group A streptococcus (GAS) pharyngitis can cause serious complications such as rheumatic heart disease. The McIsaac sore throat score is a clinical prediction score used to improve the detection rate of GAS pharyngitis.
Ching-Tang Shih   +2 more
doaj   +1 more source

Development of an Opsonophagocytic Killing Assay Using HL-60 Cells for Detection of Functional Antibodies against Streptococcus pyogenes

open access: yesmSphere, 2018
The clinical development of group A streptococcal (GAS) vaccines will require the implementation of a standardized, high-throughput assay to measure the activity of functional opsonic antibodies in vaccine recipients. In the present study, we adapted and
Sanaz Salehi   +3 more
doaj   +1 more source

The effect of hydrophobicity of group a beta-hemolytic streptococcus in the process of adherence and biofilm production [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2014
Introduction. Bacterial cell hydrophobicity and adherence to a substrate are one of the most important factors in biofilm formation. Group A streptococcus is an unstable and low biofilm productor.
Šmitran Aleksandra   +2 more
doaj   +1 more source

An Experimental Group A Streptococcus Vaccine That Reduces Pharyngitis and Tonsillitis in a Nonhuman Primate Model

open access: yesmBio, 2019
Group A Streptococcus (GAS) infections account for an estimated 500,000 deaths every year. This bacterial pathogen is responsible for a variety of mild and life-threatening infections and the triggering of chronic autoimmune sequelae.
Tania Rivera-Hernandez   +12 more
doaj   +1 more source

Concurrent Brain Subregion Microgliosis in an HLA-II Mouse Model of Group A Streptococcal Skin Infection

open access: yesMicroorganisms, 2023
The broad range of clinical manifestations and life-threatening infections caused by the Gram-positive bacterium, Streptococcus pyogenes or Group A Streptococcus (GAS), remains a significant concern to public health, with a subset of individuals ...
Suba Nookala   +3 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

HLA-II-Dependent Neuroimmune Changes in Group A Streptococcal Necrotizing Fasciitis

open access: yesPathogens, 2023
Streptococcus pyogenes (Group A Streptococcus, GAS) bacteria cause a spectrum of human diseases ranging from self-limiting pharyngitis and mild, uncomplicated skin infections (impetigo, erysipelas, and cellulitis) to highly morbid and rapidly invasive ...
Ganesh Ambigapathy   +4 more
doaj   +1 more source

Autophagy vs. Group A Streptococcus [PDF]

open access: yesAutophagy, 2006
We have identified several mammalian protein components of the autophagy pathway. By using them as powerful tools to examine the functional significance of this degradation pathway, we recently showed that autophagy efficiently kills a pathogenic bacterium, Group A Streptococcus, after it invades host cells. However, the autophagosomes induced by these
openaire   +2 more sources

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