Results 51 to 60 of about 260,732 (267)

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source

Phylogenetic relationship of prophages is affected by CRISPR selection in Group A Streptococcus

BMC Microbiology, 2019
Background Group A Streptococcus (GAS) is a major human pathogen, which is associated with a wide spectrum of invasive diseases, such as pharyngitis, scarlet fever, rheumatic fever, and streptococcal toxic shock syndrome (STSS).
Shunsuke Yamada, Masaki Shibasaki, Kazunori Murase, Takayasu Watanabe, Chihiro Aikawa, Takashi Nozawa, Ichiro Nakagawa   +6 more
doaj   +1 more source

Bubble Formation Control: Fabrication of Centimeter‐Sized Tissue‐Like Constructs by Catalase‐Coated Oxygen‐Releasing Hydrogel

Advanced Materials, EarlyView.
Oxygen‐releasing hydrogels are widely used to support cell survival in 3D cultures and to promote wound healing. However, incorporating catalase to convert H2O2 into O2 often generates additional oxygen bubbles, leading to material instability which rarely addressed.
Sukulya Bunuasunthon, Isabel F. Amaral, Ana P. Pêgo, Michiya Matsusaki   +3 more
wiley   +1 more source

Additive‐Manufactured, Multifunctional Bioreactor Technology for Dynamic Culture of 3D Bioprinted Tissue Models

Advanced Materials Technologies, EarlyView.
We introduce an additively manufactured bioreactor with a perfusion flow system and integrated temperature and pH sensors for skeletal muscle tissue biofabrication. The bioreactor's performance was evaluated by assessing the viability, spreading of the myoblast cells in a printed scaffold, and contraction of the isolated murine musculi interossei ...
Lys Sprenger, Johann Schorzmann, Hsuan‐Heng Lu, Muhammad Osama, Julian Bauer, Michael Haug, Oliver Friedrich, Aldo R. Boccaccini, Frank Döpper, Sahar Salehi   +9 more
wiley   +1 more source

Sharp increase in the incidence and severity of invasive Streptococcus pyogenes infections in children after the COVID-19 pandemic (2019-2023): A nationwide multicenter study

International Journal of Infectious Diseases
Objectives: A global surge in pediatric invasive group A streptococcal infection (iGAS) was reported after autumn 2022. This study analyzed the epidemiology and severity of iGAS in Spain, comparing two periods; P1: pre-outbreak (January 2019-September ...
Elvira Cobo-Vázquez, David Aguilera-Alonso, David Grandioso-Vas, Anna Gamell, Victoria Rello-Saltor, Manuel Oltra-Benavent, Eloisa Cervantes, Francisco Sanz-Santaeufemia, Jaime Carrasco-Colom, Ángela Manzanares-Casteleiro, Laura Martín-Pedraz, Eva Ramírez de Arellano, Lola Falcón-Neira, Leticia Martínez-Campos, Elena Colino-Gil, Beatriz Jiménez-Montero, Olga Calavia, Anna Hernandez-Ventura, Elena Del Castillo-Navío, Vanesa Matías-Del Pozo, Laura Calle-Miguel, Beatriz Soto, Berta Fernández, Filip Camil-Olteanu, Marta Pareja-León, Nuria López-Segura, Fátima Ara-Montojo, Beatriz Ruiz-Sáez, Cristina Calvo-Monge, María Sánchez-Códez, Teresa Reinoso, Katie Badillo, Carmen Vázquez, Pilar Villalón, Jesús Oteo-Iglesias, Isabel Mellado-Sola, Emilia Cercenado, Daniel Blázquez-Gamero, Ana Menasalvas, Maria José González-Abad, Borja Guarch, Mercedes Ibáñez-Alcalde, Begoña Carazo, Mayli Lung, Cristina Calvo, Jesús Saavedra-Lozano   +45 more
doaj   +1 more source

3D‐Printed Corneal Substitutes: Materials, Fabrication, and Preclinical Progress

Advanced Materials Technologies, EarlyView.
Successful clinical translation of 3D‐printed corneal substitutes relies on the interplay between the bioink properties, cellular component, and the fabrication process. These factors influence the critical properties of the construct, including optical transparency, mechanical stability, suture retention, that ultimately govern long‐term stromal ...
Shadi Moshayedi, Ashley Vazquez, Alexander J. Choi, Dimitrios Karamichos, Jayoung Kim   +4 more
wiley   +1 more source

Low GAS carriage in school-aged children in western China during the national atypical scarlet fever resurgence: Insights from two cross-sectional studies

Journal of Global Antimicrobial Resistance
Introduction: This study examined group A streptococcus(GAS) carriage, emm types, and antibiotic susceptibility in children (6–13 years) in Aral, China, during the post-COVID-19 scarlet fever resurgence, providing regional insights.
Mengyang Guo, Xiangping Hou, Wei Shi, Qian Huang, Wei Gao, Limin Dong, Yun Lai, Siyu Chen, Jianghong Deng, Kaihu Yao   +9 more
doaj   +1 more source

Dissecting the Ecological Structure of Health and Disease in the Global Gut Microbiome

Advanced Science, EarlyView.
We introduce Wiredancer, a framework that identifies three continuous ecological factors of the gut microbiota. These factors exhibit distinct patterns across health and disease, jointly capturing disrupted ecological stability and offering a new perspective for precision diagnostics and therapeutic strategies.
Baoyuan Zhu, Shuhao Chen, Yunheng Diao, Wei Wang, Yuanyuan Huang, Liqin Liang, Xiaodan Lu, Rui Han, Minxin Guo, Zhaobo Li, Shuhong Wang, Hehua Li, Chenyu Liu, Jing Zhou, Dongsheng Xiong, Xiaobo Li, Yuping Ning, Xuetao Shi, Fengchun Wu, Kai Wu   +19 more
wiley   +1 more source

Rhamnose polysaccharide-decorated outer membrane vesicles as a vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Vaccine: X
Group A Streptococcus (Strep A) cause a wide range of human-exclusive infections, annually killing more than 500,000 people. Antibiotic resistance incidence of invasive Strep A tripled in the past decade and emphasises the need to develop a universal ...
Sowmya Ajay Castro, Sarah Thomson, Helen Alexandra Shaw, Azul Zorzoli, Benjamin H. Meyer, Mark Reglinski, Mark McNeil, Helge C. Dorfmueller   +7 more
doaj   +1 more source

Surrogacy in Antimicrobial Susceptibility Testing of Group A Streptococcus [Letter]

Infection and Drug Resistance, 2023
Harit Kumar,1 Nitin Kumar2 1Department of Microbiology, Maharishi Markandeshwar Institute of Medical Sciences & Research, Maharishi Markandeshwar (Deemed to be) University Mullana, Mullana, Haryana, India; 2Department of Microbiology, Xavier ...
Kumar H, Kumar N
doaj