Results 71 to 80 of about 121,872,801 (310)

A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting. [PDF]

, 2005
A 10-month longitudinal household study of pre-school children and their families was undertaken with monthly visits collecting epidemiological data and nasopharyngeal swabs in Hertfordshire, England from 2001 to 2002.
Martin, SA, Edmunds, WJ, Hussain, M, George, R, Efstratiou, A, Miller, E, Pebody, RG, Melegaro, A, Talukdar, R   +8 more
core   +1 more source

Group A Streptococcus emm Gene Types in Pharyngeal Isolates, Ontario, Canada, 2002–2010

Emerging Infectious Diseases, 2011
Group A Streptococcus (GAS) is a human-adapted pathogen that causes a variety of diseases, including pharyngitis and invasive infections. GAS strains are categorized by variation in the nucleotide sequence of the gene (emm) that encodes the M protein. To
Patrick R. Shea, Amy L. Ewbank, Javier H. Gonzalez-Lugo, Alexandro J. Martagon-Rosado, Juan C. Martinez-Gutierrez, Hina A. Rehman, Monica Serrano-Gonzalez, Nahuel Fittipaldi, Stephen B. Beres, Anthony R. Flores, Donald E. Low, Barbara M. Willey, James M. Musser   +12 more
doaj   +1 more source

Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen

Advanced Materials, EarlyView.
Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang, Amelia Hasenauer, Kristian Ivkovic, Ann‐Sophie Frind, David Fercher, Marcy Zenobi‐Wong   +5 more
wiley   +1 more source

The exploitation of human glycans by Group A Streptococcus

, 2022
Host carbohydrates, or glycans, have been implicated in the pathogenesis of many bacterial infections. Group A Streptococcus (GAS) is a Gram-positive bacterium that readily colonises the skin and oropharynx, and is a significant cause of mortality in ...
Sanderson-Smith, Martina, Indraratna, Anuk D, Skropeta, Danielle, Everest-Dass, Arun, Danielle Skropeta, Martina Sanderson-Smith, Arun Everest-Dass, Anuk D Indraratna   +7 more
core   +1 more source

A rare case of Streptococcus pyogenes vertebral osteomyelitis in a young, immunocompetent male

IDCases
Streptococcus pyogenes (Group A Streptococcus, GAS) is a well-recognized cause of invasive infections. However, it’s an uncommon etiologic microorganism in adult vertebral osteomyelitis.
Saran Lal Ajai Mokan Dasan, Balakrishnan Arivalagan, Pranav Singla, Yusra Shah, Raydi Mejia Landron, Angel Barrera Ventura   +5 more
doaj   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Region‐Specific Profiling of the Gut Microbiome and Metabolite Landscape in Response to Dietary Intervention Using Electronics‐Free Ingestible Smart Sampling Capsules

Advanced Materials Technologies, EarlyView.
Region‐specific profiling of the gut microbiome is achieved non‐invasively using electronics‐free ingestible sampling capsules that activate at defined intestinal sites through stimuli‐responsive coatings. Deployed in a porcine dietary intervention model, the capsules resolve spatially distinct, fiber‐driven shifts in microbial composition and short ...
Devendra Sarnaik, Caitlyn Sullivan, Akshay Krishnakumar, Fangxin Chen, Anna Clapp Organski, Wayne W. Campbell, Jay S. Johnson, Tzu‐Wen L. Cross, Rahim Rahimi   +8 more
wiley   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

Advanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang, Jianhua Li, Huilu Zhang, Qi Qin, Yichen Huang, Xiaofan Tian, Chao Sun, Binbin Li, Zhengxin Wang, Xin Zhang   +9 more
wiley   +1 more source

A novel integrative and conjugative element in Streptococcus pyogenes carries a cfr-like gene associated with linezolid resistance in other species

mSphere
Treatment of severe invasive Streptococcus pyogenes infections has historically relied on β-lactam antibiotics with adjunctive clindamycin. Rising rates of lincosamide resistance have led to adoption of linezolid as an alternative adjunctive therapy ...
Daniel B. Amusin, Lacy M. Simons, Dulce S. Garcia, Alan R. Hauser, Emma Office, Preeti Jaggi, David B. Williams, Larry K. Kociolek, Ami B. Patel, Stanford T. Shulman, Judith A. Guzman-Cottrill, Robert R. Tanz, Egon A. Ozer   +12 more
doaj   +1 more source

Phylogenetic relationship of prophages is affected by CRISPR selection in Group A Streptococcus

BMC Microbiology, 2019
Background Group A Streptococcus (GAS) is a major human pathogen, which is associated with a wide spectrum of invasive diseases, such as pharyngitis, scarlet fever, rheumatic fever, and streptococcal toxic shock syndrome (STSS).
Shunsuke Yamada, Masaki Shibasaki, Kazunori Murase, Takayasu Watanabe, Chihiro Aikawa, Takashi Nozawa, Ichiro Nakagawa   +6 more
doaj   +1 more source