Results 81 to 90 of about 116,012,081 (309)

Probiotic‐Derived Vesicles Rectally Delivered via Thermo‐Gelling Copolymer Promote Mucosal Healing and Reduce Inflammation in Ulcerative Colitis

Advanced Science, EarlyView.
A thermo‐responsive rectal delivery platform integrating probiotic‐derived extracellular vesicles within a hyaluronic acid‐based copolymer enables localized and sustained therapy for ulcerative colitis. The formulation effectively suppresses inflammation, promotes macrophage polarization toward a regenerative phenotype, restores epithelial barrier ...
Ayushi Mairal, Ubaid Tariq, Shreya Mehrotra, Saravanan Matheshwaran, Jan Marsal, Ashok Kumar   +5 more
wiley   +1 more source

Sharp increase in the incidence and severity of invasive Streptococcus pyogenes infections in children after the COVID-19 pandemic (2019-2023): A nationwide multicenter study

International Journal of Infectious Diseases
Objectives: A global surge in pediatric invasive group A streptococcal infection (iGAS) was reported after autumn 2022. This study analyzed the epidemiology and severity of iGAS in Spain, comparing two periods; P1: pre-outbreak (January 2019-September ...
Elvira Cobo-Vázquez, David Aguilera-Alonso, David Grandioso-Vas, Anna Gamell, Victoria Rello-Saltor, Manuel Oltra-Benavent, Eloisa Cervantes, Francisco Sanz-Santaeufemia, Jaime Carrasco-Colom, Ángela Manzanares-Casteleiro, Laura Martín-Pedraz, Eva Ramírez de Arellano, Lola Falcón-Neira, Leticia Martínez-Campos, Elena Colino-Gil, Beatriz Jiménez-Montero, Olga Calavia, Anna Hernandez-Ventura, Elena Del Castillo-Navío, Vanesa Matías-Del Pozo, Laura Calle-Miguel, Beatriz Soto, Berta Fernández, Filip Camil-Olteanu, Marta Pareja-León, Nuria López-Segura, Fátima Ara-Montojo, Beatriz Ruiz-Sáez, Cristina Calvo-Monge, María Sánchez-Códez, Teresa Reinoso, Katie Badillo, Carmen Vázquez, Pilar Villalón, Jesús Oteo-Iglesias, Isabel Mellado-Sola, Emilia Cercenado, Daniel Blázquez-Gamero, Ana Menasalvas, Maria José González-Abad, Borja Guarch, Mercedes Ibáñez-Alcalde, Begoña Carazo, Mayli Lung, Cristina Calvo, Jesús Saavedra-Lozano   +45 more
doaj   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Low GAS carriage in school-aged children in western China during the national atypical scarlet fever resurgence: Insights from two cross-sectional studies

Journal of Global Antimicrobial Resistance
Introduction: This study examined group A streptococcus(GAS) carriage, emm types, and antibiotic susceptibility in children (6–13 years) in Aral, China, during the post-COVID-19 scarlet fever resurgence, providing regional insights.
Mengyang Guo, Xiangping Hou, Wei Shi, Qian Huang, Wei Gao, Limin Dong, Yun Lai, Siyu Chen, Jianghong Deng, Kaihu Yao   +9 more
doaj   +1 more source

Potentially virulence-related extracellular proteins of Streptococcus equi [PDF]

, 2006
Equine strangles, a disease of the upper respiratory tract caused by the bacterium Streptococcus equi subspecies equi, is one of the most commonly diagnosed and serious diseases in horses. However, the molecular basis of S. equi subsp.
Lannergård, Jonas
core   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays

Advanced Science, EarlyView.
Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith, Katie L. Gelder, Lewis Hunter‐Craig, Daniel A. Bose, Timothy D. Craggs, Alison E. Twelvetrees   +5 more
wiley   +1 more source

Rhamnose polysaccharide-decorated outer membrane vesicles as a vaccine candidate targeting Group A Streptococcus from Streptococcus pyogenes and Streptococcus dysgalactiae subsp. equisimilis

Vaccine: X
Group A Streptococcus (Strep A) cause a wide range of human-exclusive infections, annually killing more than 500,000 people. Antibiotic resistance incidence of invasive Strep A tripled in the past decade and emphasises the need to develop a universal ...
Sowmya Ajay Castro, Sarah Thomson, Helen Alexandra Shaw, Azul Zorzoli, Benjamin H. Meyer, Mark Reglinski, Mark McNeil, Helge C. Dorfmueller   +7 more
doaj   +1 more source

Surrogacy in Antimicrobial Susceptibility Testing of Group A Streptococcus [Letter]

Infection and Drug Resistance, 2023
Harit Kumar,1 Nitin Kumar2 1Department of Microbiology, Maharishi Markandeshwar Institute of Medical Sciences & Research, Maharishi Markandeshwar (Deemed to be) University Mullana, Mullana, Haryana, India; 2Department of Microbiology, Xavier ...
Kumar H, Kumar N
doaj  

Generation of Bioluminescent Group A Streptococcus for Biophotonic Imaging

, 2020
Bioluminescence is a rapid and cost-saving technology that enables monitoring of bacteria in real time in animal infection models. Here, we report a method for labeling GAS with a set of plasmids we have developed and deposited with Addgene.
Jacelyn M. S. Loh, Soh, KY, Loh, JMS, Thomas Proft, Kar Yan Soh, Proft, Thomas   +5 more
core   +1 more source

From meadows to milk to mucosa – adaptation of Streptococcus and Lactococcus species to their nutritional environments [PDF]

, 2012
Lactic acid bacteria (LAB) are indigenous to food-related habitats as well as associated with the mucosal surfaces of animals. The LAB family Streptococcaceae consists of the genera Lactococcus and Streptococcus.
Kok, Jan, Zeyniyev, Araz, Kuipers, Oscar P.,, Kok, Jan,, Zeyniyev, Araz,, Price, Claire E, Price, Claire E.,, Kuipers, Oscar P, Kuipers, Oscar P; id_orcid   +8 more
core   +2 more sources