Results 61 to 70 of about 121,872,801 (310)

Streptococcus equi subsp. equi and Streptococcus equi subsp. zooepidemicus [PDF]

, 2013
The bacterium Streptococcus equi subsp. equi (S. equi) is the causative agent of the highly contagious upper respiratory disease "strangles" in horses. The ancestor of S. equi, Streptococcus equi subsp. zooepidemicus (S.
Lindahl, Susanne
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Genome specialization and decay of the strangles pathogen, Streptococcus equi, is driven by persistent infection [PDF]

, 2015
The authors would like to thank the Horserace Betting Levy Board for funding the analysis of the eqbE mutant (ref: Vet/prj/758). The Horse Trust funded the collection of isolates from UK outbreaks of strangles (G1606).
Paillot, Romain, Waller, Andrew S, Steward, Karen F, Robinson, Carl, Holden, Matthew T G, Harris, Simon R, Parkhill, Julian, Webb, Katy S, Holden, Matthew T G; id_orcid   +8 more
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Contribution of fibronectin-binding protein to pathogenesis of Streptococcus suis serotype 2 [PDF]

, 2002
In the present study we investigated the role of the fibronectin (FN)- and fibrinogen (FGN)-binding protein (FBPS) in the pathogenesis of Streptococcus suis serotype 2 in piglets. The complete gene encoding FBPS from S.
Dijkstra, J., Smit, H.E., Verhaar, R., Alphen, L., van, Greeff, A., de, Robin Verhaar, Loek van Alphen, Herma Buys, Buys, H., Janny Dijkstra, Hilde E. Smith, Astrid de Greeff   +11 more
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Peptide-Protein Conjugation and Characterization to Develop Vaccines for Group A Streptococcus

, 2021
Peptide conjugates have been widely used for developing vaccines that prevent common bacterial infections for which peptides alone are either ineffective or provide only short-term protection. Among several carrier proteins, diphtheria toxoid and CRM197 (
Manisha Pandey, Good, Michael F, Pandey, Manisha, Sharareh Eskandari, Michael F. Good, Eskandari, Sharareh   +5 more
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Pathogenesis of Hypervirulent Group A Streptococcus [PDF]

Japan Journal of Medicine, 2018
Group A Streptococcus (GAS) causes common pharyngitis and skin infections and occasional severe invasive infections. This review describes the recent progress on the pathogenesis of hypervirulent GAS. CovRS mutations are frequent among invasive GAS isolates and lead to hypervirulence. GAS CovRS mutants can be selected in vivo by neutrophils.
Mengyao, Liu, Benfang, Lei
openaire   +2 more sources

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Identification and characterization of two temperature-induced surface-associated proteins of Streptococcus suis with high homologies to members of the arginine deiminase system of Streptococcus pyogenes [PDF]

, 2002
The present study was performed to identify stress-induced putative virulence proteins of Streptococcus suis. For this, protein expression patterns of streptococci grown at 32, 37, and 42°C were compared by one- and two-dimensional gel electrophoresis ...
Gruening, P., Smith, H.E., Winterhoff, N., Valentin-Weigand, P., Goethe, R., Kalisz, H., Rohde, M.   +6 more
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Metabolic and Fluid Biomarkers Support Microglia Activation in Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Amyotrophic lateral sclerosis is an incurable neurodegenerative disease involving motor neuron degeneration and metabolic and immune dysfunction. We combined clinical data, cerebrospinal fluid biomarkers and fluorodeoxyglucose positron emission tomography with magnetic resonance imaging to investigate the role of reactive microglia in disease ...
Matteo Zanovello, Francesca Serani, Alen Bebeti, Federica Paredi, Giulia Quadrio, Andrea Fortuna, Giacomo Maria Minicuci, Elena Pegoraro, Annachiara Cagnin, Diego Cecchin, Gianni Sorarù   +10 more
wiley   +1 more source

Emergence of respiratory Streptococcus agalactiae isolates in cystic fibrosis patients [PDF]

, 2009
Streptococcus agalactiae is a well-known pathogen for neonates and immunocompromized adults. Beyond the neonatal period, S. agalactiae is rarely found in the respiratory tract. During 2002–2008 we noticed S. agalactiae in respiratory secretions of 30/185
Vera Eickel, Brandt Claudia, Kahl, Barbara, Barbara Spellerberg, Reinisch Beatrice, Eickel, Vera, Angelika Dübbers, Eickel Vera, Peter Küster, Dübbers, Angelika, Brandt, Claudia, Küster Peter, Reinisch, Beatrice, Beatrice Reinisch, Dübbers Angelika, Spellerberg Barbara, Küster, Peter, Kahl Barbara, Barbara Kahl, Claudia Brandt, Spellerberg, Barbara   +20 more
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