Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Group Dynamics and Allocation of Advanced Heart Failure Therapies-Heart Transplants and Ventricular Assist Devices-By Gender, Racial, and Ethnic Group. [PDF]
J Am Heart Assoc, 2023 Breathett K +13 more
europepmc +1 more source
Herding dynamics in exchange groups: Evidence from Euronext
, 2014 Fotini Economou +3 more
openalex +2 more sources
Dynamics in the Kepler problem on the Heisenberg group [PDF]
, 2023 S. G. Basalaev, S. V. Agapov
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
The Effects of Rudeness on NICU Medical Teams Studied by a New Tool for the Assessment of Decision-Making Group Dynamics. [PDF]
Children (Basel), 2022 Riskin Y +6 more
europepmc +1 more source
Dynamics of Groups around Interacting Double Ellipticals: Measuring Dark Matter Haloes [PDF]
, 1990 H. Quintana
openalex +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Toward Understanding Polar Heat Transport Enhancement in Subglacial Oceans on Icy Moons
Geophysical Research LettersThe interior oceans of several icy moons are considered as affected by rotation. Observations suggest a larger heat transport around the poles than at the equator.
Robert Hartmann +3 more
doaj +1 more source