Results 121 to 130 of about 13,685,848 (310)
Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy
FEBS Letters, EarlyView.The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley +1 more source
Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex
Nature CommunicationsThe BTRR (BLM/TOP3A/RMI1/RMI2) complex resolves DNA replication and recombination intermediates to maintain genome stability. Alongside PICH, they target mitotic DNA intertwinements, known as ultrafine DNA bridges, facilitating chromosome segregation ...
María Fernández-Casañas +8 more
doaj +1 more source
General Dynamics Corporation Report GA-1612
, 1960 From preface: This report presents the status of design of the MGCR prototype plant as of July 1 ...
General Dynamics Corporation
core
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
FEBS Letters, EarlyView.This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Antea Group Archeologie 2015/69
, 2015 In opdracht van de gemeente Valkenswaard heeft Antea Group in mei en juni 2015 een archeologisch bureauonderzoek uitgevoerd. Dit in het kader van een bestemmingsplanwijziging van het terrein ter hoogte van de Pastoor Heerkensdreef 29 in Valkenswaard.
Sophie, G. (Antea Group), G. Sophie
core +1 more source
Comparing the paths of Hedgehog release in artificial and natural settings
FEBS Letters, EarlyView.Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
, 1968 Biweekly newsletter published for employees of the General Dynamics Fort Worth Division containing work-related information, updates about employees, and other ...
General Dynamics Corporation. Convair Division.
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How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
FEBS Letters, EarlyView.In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Editorial: Group dynamics and redistributive policy preferences in the Global South. [PDF]
Front Sociol, 2023 Steele LG, Breznau N.
europepmc +1 more source