Results 61 to 70 of about 13,685,848 (310)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
STAG2 loss in Ewing sarcoma alters enhancer-promoter contacts dependent and independent of EWS::FLI1
EMBO ReportsCohesin complexes carrying STAG1 or STAG2 organize the genome into chromatin loops. STAG2 loss-of-function mutations promote metastasis in Ewing sarcoma, a pediatric cancer driven by the fusion transcription factor EWS::FLI1. We integrated transcriptomic
Daniel Giménez-Llorente +6 more
doaj +1 more source
A review of pedestrian group dynamics and methodologies in modelling pedestrian group behaviours [PDF]
, 2014 Observations conducted by researchers revealed that the group interaction within crowds is a common phenomenon and has great influence on pedestrian behaviour.
Yarlagadda, Prasad K. +3 more
core
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Temporal pairwise spike correlations fully capture single-neuron information
Nature Communications, 2016 To understand the neural code it is important to determine what spiking features contain the relevant information. Here, the authors use mathematical approaches to show that two pair-wise correlation functions, the autocorrelation function within spike ...
Amadeus Dettner +2 more
doaj +1 more source
Frontiers in Built Environment, 2017 The current work introduces a novel combination of two Bayesian tools, Gaussian Processes (GPs), and the use of the Approximate Bayesian Computation (ABC) algorithm for kernel selection and parameter estimation for machine learning applications.
Anis Ben Abdessalem +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Scientific ReportsHydrological studies depend heavily on environmental variables, such as precipitation and resulting runoff, which exhibit highly seasonal and intermittent behaviour in semiarid basins.
Marina Cantalejo +3 more
doaj +1 more source
Proposal for demonstration of long-range cluster state entanglement in the presence of photon loss
APL Photonics, 2017 Photonic cluster states are a crucial resource for optical quantum computing. Recently a quantum dot single photon source has been demonstrated to produce strings of single photons in a small linear cluster state.
Thomas Nutz +3 more
doaj +1 more source