Results 71 to 80 of about 13,685,848 (310)

Antea Group Archeologie 2020/72

open access: yes, 2019
Auteurs: R. Fens & I. Fleuren rapportvolgnummer: 2020/72 Antea Group projectnummer 271507 ARCHIS-nr 4856764100 Het plangebied ligt langs de voormalige Zuiderzeekust. De vestingstad Muiden, een van oorsprong middeleeuwse stad, bevindt zich aan de monding
Koopmanschap, H (Antea Group)   +30 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Interactions between the discoidin domain receptor 1 and β1 integrin regulate attachment to collagen

open access: yesBiology Open, 2013
Summary Collagen degradation by phagocytosis is essential for physiological collagen turnover and connective tissue homeostasis. The rate limiting step of phagocytosis is the binding of specific adhesion receptors, which include the integrins and ...
Lisa A. Staudinger   +7 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Dynamics of Groups Online

open access: yes, 2020
This chapter outlines how online groups form and regulate themselves. It examines the dynamics of online groups compared to their offline counterparts, focusing on why online group membership is an attractive option for many people, especially in today’s digital age. Specifically, the chapter addresses topics such as how roles, norms and group identity
openaire   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Group dynamics and software engineering [PDF]

open access: yes, 1999
This paper reports on an experiment that was conducted to determine the extent to which group dynamics impacts on the effectiveness of software development teams.
Thomas, Richard, Thomas, Richard N.
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

On calculating structural similarity metrics in population-based structural health monitoring

open access: yesData-Centric Engineering
The newly introduced discipline of Population-Based Structural Health Monitoring (PBSHM) has been developed in order to circumvent the issue of data scarcity in “classical” SHM.
Daniel S. Brennan   +3 more
doaj   +1 more source

Antea Group Archeologie 2018/188

open access: yes, 2020
In november 2018 heeft Antea Group een archeologisch bureauonderzoek uitgevoerd ten behoeve van de aanleg van een warmteleiding in Leeuwarden-Zuid, gemeente Leeuwarden. Na afloop van dit onderzoek hebben twee tracéwijzigingen plaatsgevonden. Na de eerste
Fens, R. (Antea Group)   +3 more
core   +1 more source

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