Results 91 to 100 of about 2,704,826 (264)

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

Commitment and Desire in Sharon Hayes’s Ricerche: three 2013

open access: yesTate Papers, 2016
This article examines Sharon Hayes’s video work Ricerche: three 2013 and the way it represents and mediates the often-painful psychic processes of group formation, in this case propelled by internal and external social pressures. Drawing upon the work of
Larne Abse Gogarty
doaj  

Solvated PbI2 Clusters Preceding the Crystallization of Lead Halide Perovskites–a UV/VIS In Situ Study

open access: yesAdvanced Electronic Materials
The solution‐based fabrication of reproducible, high‐quality lead iodide perovskite films demands a detailed understanding of the crystallization dynamics, which is mainly determined by the perovskite precursor solution and its processing conditions.
Maximilian Spies   +4 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Distinct decision-making properties underlying the species specificity of group formation of flies. [PDF]

open access: yesR Soc Open Sci, 2022
Shirasaki R   +5 more
europepmc   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Permissive aggregative group formation favors coexistence between cooperators and defectors in yeast. [PDF]

open access: yesISME J, 2022
Belpaire TER   +6 more
europepmc   +1 more source

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