Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Thermal emission spectra provide key insights into the atmospheric composition and especially the temperature structure of an exoplanet. With broader wavelength coverage, sensitivity, and higher resolution, JWST has enabled robust constraints on these ...
Tonmoy Deka +6 more
doaj +1 more source
The Sticky Resting Box, a new tool for studying resting behaviour of Afrotropical malaria vectors
Background Monitoring densities of adult mosquito populations is a major challenge in efforts to evaluate the epidemiology of mosquito-borne diseases, and their response to vector control interventions.
Marco Pombi +9 more
doaj +1 more source
Identifying the social context of single- and mixed-species group formation in large African herbivores. [PDF]
Saltz JB, Palmer MS, Beaudrot L.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Addressing the challenge of efficient gas control in high-gas coal mines with ultra-long panels, this study focuses on the No. 8 coal seam in the Baode Mine.
Shuaiyin He +5 more
doaj +1 more source
Sedimentary lithofacies, petrography and diagenesis of the Kapuni group in the Kapuni Field, Taranaki Basin, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science with Honours in Earth Science at Massey University, Palmerston North, New Zealand [PDF]
The reservoir architecture and quality of the Kapuni Group sandstones in seven wells (Kapuni−1, −3, −8, −12, Deep−1, 14 and −15) in the Kapuni Field are characterised using available core and digital geophysical log data.
Cooper, Brent John
core
Habitat partitioning, co-occurrence patterns, and mixed-species group formation in sympatric delphinids. [PDF]
Syme J, Kiszka JJ, Parra GJ.
europepmc +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source

