Results 111 to 120 of about 6,393,807 (299)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

A Next-generation Exoplanet Atmospheric Retrieval Framework NEXOTRANS for Emission Spectroscopy: New Constraints and Atmospheric Characterization of WASP-69 b Using JWST NIRCam and MIRI Observations

open access: yesThe Astrophysical Journal
Thermal emission spectra provide key insights into the atmospheric composition and especially the temperature structure of an exoplanet. With broader wavelength coverage, sensitivity, and higher resolution, JWST has enabled robust constraints on these ...
Tonmoy Deka   +6 more
doaj   +1 more source

The Sticky Resting Box, a new tool for studying resting behaviour of Afrotropical malaria vectors

open access: yesParasites & Vectors, 2014
Background Monitoring densities of adult mosquito populations is a major challenge in efforts to evaluate the epidemiology of mosquito-borne diseases, and their response to vector control interventions.
Marco Pombi   +9 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Delineation and Application of Gas Geological Units for Optimized Large-Scale Gas Drainage in the Baode Mine

open access: yesEnergies
Addressing the challenge of efficient gas control in high-gas coal mines with ultra-long panels, this study focuses on the No. 8 coal seam in the Baode Mine.
Shuaiyin He   +5 more
doaj   +1 more source

Sedimentary lithofacies, petrography and diagenesis of the Kapuni group in the Kapuni Field, Taranaki Basin, New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science with Honours in Earth Science at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2004
The reservoir architecture and quality of the Kapuni Group sandstones in seven wells (Kapuni−1, −3, −8, −12, Deep−1, 14 and −15) in the Kapuni Field are characterised using available core and digital geophysical log data.
Cooper, Brent John
core  

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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