Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Backbone Engineering of Benzodifurandione‐Based n‐Type OMIECs With Antiambipolar Behavior
Advanced Electronic MaterialsOrganic mixed ionic‐electronic conductors (OMIECs) are key components for the next‐generation bioelectronics, albeit with n‐type materials remaining significantly underrepresented compared to their p‐type counterparts. Furthermore, reaching low operating
Dilara Gunturkun +5 more
doaj +1 more source
Functional Switch and Ethyl Group Formation in the Bacterial Polytrichastrene Synthase from Chryseobacterium polytrichastri. [PDF]
Angew Chem Int Ed Engl, 2021 Hou A, Goldfuss B, Dickschat JS.
europepmc +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Group formation and competition: instrumental and expressive approaches
, 2001 We construct models of group formation designed to capture some of the key features of political and social competition. The models draw on the ‘citizen candidate’ approach and allow competition to be modelled as either compromise - where all groups ...
Jennings, Colin, Hamlin, Alan
core +1 more source
Social Behavior and Group Formation in Male Asian Elephants (Elephas maximus): The Effects of Age and Musth in Wild and Zoo-Housed Animals. [PDF]
Animals (Basel), 2022 LaDue CA +3 more
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Fest, ritual og myte fra et socialontologisk og fra et neurosociologisk perspektiv
Religionsvidenskabeligt TidsskriftENGLISH ABSTRACT: In recent years, new research has emerged that support Emile Durkheim's claim about the existence of collective consciousness and effervescence from different angles.
Niels Reeh
doaj
The Astrophysical JournalThe advent of JWST has marked a new era in exoplanetary atmospheric studies, offering higher-resolution data and greater precision across a broader spectral range than previous space-based telescopes.
Tonmoy Deka +5 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source