Results 161 to 170 of about 15,576,726 (307)

Antea Group Archeologie 2015/128

open access: yes, 2017
In september 2015 heeft Antea Group een inventariserend archeologisch booronderzoek (verkennende fase) uitgevoerd aan de Pastoor Heerkensdreef in Valkenswaard in het kader van een bestemmingsplanwijziging. Dit onderzoek volgt op een eerder uitgevoerd en
Sophie, G. (Antea Group)
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Study on fracture propagation characteristics of hydraulic fracturing in steeply inclined coal reservoirs

open access: yesMeikuang Anquan
Due to the rapid changes in burial depth in steeply inclined reservoirs (SICR), there is a significant change in stress in the up-dip and down-dip directions within the drainage range of CBM wells, and the expansion of fracturing fractures is different ...
Junqiang KANG   +5 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

Group formation and competition: instrumental and expressive approaches [PDF]

open access: yes
We construct models of group formation designed to capture some of the key features of political and social competition. The models draw on the ‘citizen candidate’ approach and allow competition to be modelled as either compromise - where all groups ...
Jennings, Colin, Hamlin, Alan
core  

Antea Group Archeologie 2018/8

open access: yes, 2018
In november/december 2017 (Haven 8-West) en februari 2018 (Haven 8-Oost) is door Antea Group in opdracht van de gemeente Waalwijk een inventariserend veldonderzoek, met proefsleuven. Dit voor het plangebied Haven 8 te Waalwijk.
Koopmanschap, Dr. H.J.L.C. (Antea Group)
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

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