Results 81 to 90 of about 24,815,163 (243)

A CONTRIBUTION TO THE DEBATE ON SCIENCE AND FAITH BY CHRISTIAN STUDENTS FROM ABIDJAN

open access: yesZygon, 2017
The science and faith debate is dominated by Western voices. In order to enrich this debate, the authors study the discourses of different groups of Christian academics and master's students in francophone Africa.
doaj   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

The Model House

open access: yes, 2011
The model house can be used for a variety of purposes. The documents and videos contain a comprehensive list of applications for the model in basic skills and key skills course, as well as a suggested list of resources for using the model, and learning ...
LSN   +2 more
core  

Antea Group Archeologie 2016/135

open access: yes, 2016
Op basis van het bureauonderzoek kan worden geconcludeerd dat binnen delen van het plangebied archeologische resten uit de middeleeuwen en de nieuwe tijd aanwezig kunnen zijn, met name aan de Kwakelkade en Friese Weg.
Teekens, drs. P.C. (Antea Group)
core   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Antea Group Archeologie 2020/75

open access: yes, 2021
Antea Group projectnummer 412729 In mei 2020 heeft Antea Group in opdracht van de opdrachtgever een archeologisch onderzoek uitgevoerd voor het plangebied ‘T020_08_AN’ te Bergen op Zoom, gemeente Bergen op Zoom.
Jong, M. de (Antea Group)
core   +1 more source

Uncovering the Dynamic System Driving Older Adults' Vitality: A Causal Loop Diagram Co‐Created With Dutch Older Adults

open access: yesHealth Expectations
Background Most studies on older adults' vitality focus on linear connections between determinants and outcomes. To design more comprehensive and impactful approaches to support the vitality of older adults, a better understanding of the interplay among ...
Djoeke Besselink   +7 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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