Results 81 to 90 of about 26,527,691 (283)

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Antea Group Archeologie 2015/69

open access: yes, 2017
In opdracht van de gemeente Valkenswaard heeft Antea Group in mei en juni 2015 een archeologisch bureauonderzoek uitgevoerd. Dit in het kader van een bestemmingsplanwijziging van het terrein ter hoogte van de Pastoor Heerkensdreef 29 in Valkenswaard.
Sophie, G. (Antea Group)
core   +1 more source

Could work-related muscle activity explain sex differences in neck pain? A meta-analysis of a pooled dataset

open access: yesScandinavian Journal of Work, Environment & Health
OBJECTIVES: Sustained activity of the upper trapezius muscle during work has been linked to the development of neck pain. Women have higher occurrences of neck pain than men, even in the same occupations.
Markus Koch   +10 more
doaj   +1 more source

Developing a Proof-of-Concept Selection Test for Entry into Primary Teacher Education Programs

open access: yesInternational Journal of Assessment Tools in Education, 2017
The purpose of this article is to report on thedevelopment of a proof-of-concept situational judgment test (SJT) to assist inthe selection of candidates for primary teacher education (ITE) programs.
Robert Klassen   +7 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Organisational and group antecedents of work group service innovativeness

open access: yes, 2009
This study examined the individual and combined effects of the organisational-level variables of climate and task design, and the group-level variables of group citizenship behaviour (GCB), market orientation, group self-efficacy (GSE), and group climate
Nsenduluka, Evaristo, Shee, Himanshu
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Antea Group Archeologie 2020/220

open access: yes, 2021
Antea Group projectnummer 412729 In november 2020 heeft Antea Group in opdracht van de opdrachtgever een archeologisch onderzoek uitgevoerd voor het plangebied ‘Heijningen Oost’, gemeente Moerdijk.
Looveren, V. van (Antea Group)
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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