Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Characterization of the complete mitochondrial genome data of the allotriploid grouper <i>Epinephelus fuscoguttatus</i> ♀× <i>Epinephelus tukula</i> ♂. [PDF]
Li Z +15 more
europepmc +1 more source
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
An ANN-based non-destructive model for age and maturity estimation of the data-deficient Goldblotch Grouper (<i>Epinephelus costae</i>): a practical tool for data-poor fisheries in conflict-affected Mediterranean coasts. [PDF]
Hamwi NI.
europepmc +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Contrastive learning for passive acoustic monitoring: A framework for sound source discovery and cross-site comparison in marine soundscapes. [PDF]
Acs R +3 more
europepmc +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Trypanosomes of fish as an emerging threat to aquaculture systems in China. [PDF]
Wang JF, Li XT, Lukeš J, Lai DH.
europepmc +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Viral Encephalopathy and Retinopathy in Dusky Groupers (Epinephelus marginatus, Lowe 1834) from Two Marine Protected Areas of the Northern Mediterranean Sea. [PDF]
Volpe E +9 more
europepmc +1 more source

