Results 141 to 150 of about 5,873,812 (294)

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu   +11 more
wiley   +1 more source

Studies on the Growth of TissuesIn Vitro [PDF]

open access: bronze, 1937
F. Jacoby, O. A. Trowell, E. N. Willmer
openalex   +1 more source

Growth and Growth Charts in Children [PDF]

open access: yesJAMA Pediatrics, 2018
Lindsay A. Thompson, Megan A. Moreno
openaire   +3 more sources

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

open access: yesMolecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Cognitive loopholes of crime: Mapping the Codevelopment of moral disengagement within perceptions of risks and rewards. [PDF]

open access: yesJ Res Adolesc
Decrop R   +8 more
europepmc   +1 more source

On the cytology of malignant growths

open access: bronze, 1906
J. BRETLAND FARMER   +2 more
openalex   +1 more source

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