Results 181 to 190 of about 400,493 (285)

Efficacy and Safety Assessment of 5‐Fluorouracil, Irinotecan and Oxaliplatin‐Loaded Implants in Mouse and Pig Models for Pancreatic Cancer Therapy

Advanced Materials, EarlyView.
A novel FIRINOX‐loaded implant demonstrates controlled drug release, and potent therapeutic efficacy in pancreatic ductal adenocarcinoma mouse models with safety confirmed in a large‐animal pre‐clinical model. This innovative drug delivery platform offers a promising new treatment approach for non‐resectable, treatment‐resistant pancreatic cancer ...
Samantha J. Wade, Ashna A. Kumar, Samuel O. Nitschke, Paul Joyce, Elahe Minaei, Stephanie E. Reuter Lange, Chelsea Penney, Holly Warren, Ruby Shepherd, Jeremy N. Dinoro, Gordon G. Wallace, Anthony Dosseto, Sameera Ansar, Naila Islam, Alistair Lochhead, George Sharbeen, Phoebe A. Phillips, Morteza Aghmesheh, Wayne J. Hawthorne, Kara L. Vine‐Perrow   +19 more
wiley   +1 more source

AI–Guided 4D Printing of Carnivorous Plants–Inspired Microneedles for Accelerated Wound Healing

Advanced Materials, EarlyView.
This work presents an artificial intelligence (AI)‐guided 4D‐printed microneedle platform inspired by carnivorous plants for wound healing. A thermo‐responsive shape memory polymer enables body temperature–triggered self‐coiling for autonomous wound closure.
Hyun Lee, Moon‐Jo Kim, DongEung Kim, Chan Ho Moon, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Junhyub Jeon, Junhyuk Son, Munwon Lim, Minho Kang, Dong Yun Lee, Donghyun Lim, Jung‐Hoon Park, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Kisuk Yang, Yunho Jeong, Youngho Eom, Hyun‐Do Jung   +21 more
wiley   +1 more source

Efficient Self‐Cleaning and Anti‐Bacterial Behavior Realized by Hierarchical Structure in Hybrid Waterborne Polyurethane Coatings Containing Photocatalyst

Advanced Materials Interfaces, EarlyView.
Hybrid WPU coatings with a hierarchical structure are constructed by first directional freezing polymerization of degradable hydrogels with a vertical channel structure and then filling these channels with aqueous WPU solution containing carbon nitride (g‐C3N4) nanosheets.
Xiaobei Zhou, Jing Xu, Jie Yu, Jie Liu, Meiqun Hu, Lie Zhao, Peter Müller‐Buschbaum, Dongming Qi, Qi Zhong   +8 more
wiley   +1 more source

From Copper Nanoparticles to Alumina Encapsulated Porous Layers With Enhanced Mechanical Stability

Advanced Materials Interfaces, EarlyView.
This study analyzes the synthesis‐structure relation of individual Cu nanoparticles and highly porous nanoparticle‐based Cu films using different sputtering‐based nanoparticle sources. The inherent mechanical instability of the films is tackled with Al2O3 encapsulation through atomic layer deposition, enabling 4‐fold increase in critical force in ...
Dominik Gutnik, Daniele Casari, Laszlo Pethö, Michael Burtscher, Anna M. Hofer‐Roblyek, Christian Mitterer, Barbara Putz   +6 more
wiley   +1 more source

A Comprehensive Review of Waste‐Derived Materials for Solar Still Performance Enhancement

Advanced Materials Interfaces, EarlyView.
ABSTRACT Solar desalination reduces energy use and produces freshwater sustainably, but its productivity is limited and cannot meet rising demand. Thus, solar desalination system improvements are sought to boost water productivity. Waste materials are abundantly available and burden the environment, making them low‐cost enhancers for solar desalination
A. S. Abdullah, Abanob Joseph, Wissam H. Alawee, Gamal B. Abdelaziz, Mohammed El Hadi Attia, Swellam W. Sharshir, Ahmed El‐Harairy   +6 more
wiley   +1 more source

Light‐Programmable Interfaces: From Molecular Photoswitching to Adaptive Membrane Separations

Advanced Materials Interfaces, EarlyView.
This review advances an interface‐centered framework for light‐responsive membranes, linking molecular photoswitches (azobenzene (AZO), spiropyran (SP), diarylethene (DAE), donor–acceptor Stenhouse adducts (DASA), photoacid) to integration strategies in polymeric, porous, self‐assembled, and mixed‐matrix systems.
Liangliang Zhang, Senlin Gu, Jianyang Zhao, Xiaojuan Hao, Lu Hua Li, Jihua Li, Lingxue Kong   +6 more
wiley   +1 more source

Ketamine impairs growth cone and synaptogenesis in human GABAergic projection neurons via GSK-3β and HDAC6 signaling. [PDF]

Mol Psychiatry
Li X, Saiyin H, Chen X, Yu Q, Ma L, Liang W.   +5 more
europepmc   +1 more source

3D Printing of Highly Dense and Translucent Zirconia Parts for Dental Applications: Effect of Filament Overlapping

Advanced Materials Technologies, EarlyView.
This study formulated a 5Y‐PSZ zirconia paste for extrusion‐based additive manufacturing via direct ink writing, producing dense ceramic structures for dental applications. A colloidal approach with 47 vol% nanometric powder and tailored additives optimized rheology and printability.
Juliana de Freitas Gouveia Silva, Manuel Fellipe Rodrigues Pais Alves, Ana Carolina da Silva, Tiago Moreira Bastos Campos, Renata Marques De Melo, Susana Maria Henriques Olhero   +5 more
wiley   +1 more source

Architecture of an All‐In‐One Microfluidic Platform for Accelerated Cancer Seeding, Enhanced Spheroid Formation, and Dynamic Drug Screening Trials

Advanced Materials Technologies, EarlyView.
An all‐in‐one microfluidic platform consists of two‐layered PDMS channels integrated with a hydrogel microwell array. This platform enables flow‐driven tumor cell capture, enhanced spheroid formation within the microwells, and advective drug testing. ABSTRACT Effective cancer drug screening requires platforms that replicate the physiological complexity
Omar M. Rahman, Shengxi Lan, Dae Kun Hwang   +2 more
wiley   +1 more source

The oligodendrocyte growth cone and its actin cytoskeleton: A fundamental element for progenitor cell migration and CNS myelination. [PDF]

Glia, 2020
Thomason EJ, Escalante M, Osterhout DJ, Fuss B.   +3 more
europepmc   +1 more source