Results 1 to 10 of about 50,714 (254)

microRNAs in axon guidance [PDF]

Frontiers in Cellular Neuroscience, 2014
Brain wiring is a highly intricate process in which trillions of neuronal connections are established. Its initial phase is particularly crucial in establishing the general framework of neuronal circuits.
Marie-Laure Michele Baudet, Anais Bellon   +1 more
exaly   +5 more sources

Exosomes: new targets for understanding axon guidance in the developing central nervous system [PDF]

Frontiers in Cell and Developmental Biology
Axon guidance is a key event in neural circuit development that drives the correct targeting of axons to their targets through long distances and unique patterns.
Mingyu Liu, Mingyu Liu, Teng Teng, Teng Teng, Teng Teng   +4 more
exaly   +4 more sources

Axon Guidance Molecules and Pain [PDF]

Cells, 2022
Chronic pain is a debilitating condition that influences the social, economic, and psychological aspects of patients’ lives. Hence, the need for better treatment is drawing extensive interest from the research community.
Elisa Damo, Manuela Simonetti
doaj   +2 more sources

The role of axon guidance molecules in the pathogenesis of epilepsy [PDF]

Neural Regeneration Research
Current treatments for epilepsy can only manage the symptoms of the condition but cannot alter the initial onset or halt the progression of the disease. Consequently, it is crucial to identify drugs that can target novel cellular and molecular mechanisms
Zheng Liu, Chunhua Pan, Hao Huang
doaj   +2 more sources

Dopaminergic axon guidance: which makes what?

Frontiers in Cellular Neuroscience, 2012
Mesotelencephalic pathways in the adult central nervous system have been studied in great detail because of their implication in major physiological functions as well as in psychiatric, neurological and neurodegenerative diseases.
Afsaneh Gaillard, Mohamed Jaber, Gaillard Afsaneh   +2 more
exaly   +3 more sources

Signaling Mechanisms in Cortical Axon Growth, Guidance, and Branching

Frontiers in Neuroanatomy, 2011
Precise wiring of cortical circuits during development depends upon axon extension, guidance and branching to appropriate targets. Motile growth cones at axon tips navigate through the nervous system by responding to molecular cues, which modulate ...
B Ian Hutchins, Katherine Kalil
exaly   +3 more sources

Roundabout receptor signaling: beyond axon guidance [PDF]

Signal Transduction and Targeted Therapy
Naresh L. Selokar, Wilfried A. Kues
doaj   +2 more sources

Multiple Functions of Draxin/Netrin-1 Signaling in the Development of Neural Circuits in the Spinal Cord and the Brain

Frontiers in Neuroanatomy, 2021
Axon guidance proteins play key roles in the formation of neural circuits during development. We previously identified an axon guidance cue, named draxin, that has no homology with other axon guidance proteins.
Giasuddin Ahmed, Yohei Shinmyo
doaj   +1 more source

Endoglycan plays a role in axon guidance by modulating cell adhesion

eLife, 2021
Axon navigation depends on the interactions between guidance molecules along the trajectory and specific receptors on the growth cone. However, our in vitro and in vivo studies on the role of Endoglycan demonstrate that in addition to specific guidance ...
Thomas Baeriswyl, Alexandre Dumoulin, Martina Schaettin, Georgia Tsapara, Vera Niederkofler, Denise Helbling, Evelyn Avilés, Jeannine A Frei, Nicole H Wilson, Matthias Gesemann, Beat Kunz, Esther T Stoeckli   +11 more
doaj   +1 more source

Cbln1 regulates axon growth and guidance in multiple neural regions.

PLoS Biology, 2022
The accurate construction of neural circuits requires the precise control of axon growth and guidance, which is regulated by multiple growth and guidance cues during early nervous system development.
Peng Han, Yuanchu She, Zhuoxuan Yang, Mengru Zhuang, Qingjun Wang, Xiaopeng Luo, Chaoqun Yin, Junda Zhu, Samie R Jaffrey, Sheng-Jian Ji   +9 more
doaj   +1 more source