Results 21 to 30 of about 902,976 (291)

A network of HSPG core proteins and HS modifying enzymes regulates netrin-dependent guidance of D-type motor neurons in Caenorhabditis elegans.

PLoS ONE, 2013
Heparan sulfate proteoglycans (HSPGs) are proteins with long covalently attached sugar side chains of the heparan sulfate (HS) type. Depending on the cellular context HS chains carry multiple structural modifications such as sulfate residues or ...
Stephan Gysi, Christa Rhiner, Stephane Flibotte, Donald G Moerman, Michael O Hengartner   +4 more
doaj   +1 more source

Topographically specific effects of ELF-1 on retinal axon guidance in vitro and retinal axon mapping in vivo [PDF]

, 1996
Peer ...
Cheng, Hwai-Jong, Hansen, Michael J., Yoon, Cliff H., O'Leary, Dennis D.M, Nakamoto, Masaru, Hansen, Michael J, Yoon, Cliff H, O'Leary, Dennis D.M., Flanagan, John G, Flanagan, John G., Friedman, Glenn C, Friedman, Glenn C., McLaughlin, Tod, McLaughlin, Todd   +13 more
core   +1 more source

The Atypical Rho GTPase CHW-1 Works with SAX-3/Robo To Mediate Axon Guidance in Caenorhabditis elegans

G3: Genes, Genomes, Genetics, 2018
During development, neuronal cells extend an axon toward their target destination in response to a cue to form a properly functioning nervous system.
Jamie K. Alan, Sara K. Robinson, Katie L. Magsig, Rafael S. Demarco, Erik A. Lundquist   +4 more
doaj   +1 more source

Transient axonal glycoprotein-1 (TAG-1) and laminin-α1 regulate dynamic growth cone behaviors and initial axon direction in vivo

Neural Development, 2008
Background How axon guidance signals regulate growth cone behavior and guidance decisions in the complex in vivo environment of the central nervous system is not well understood.
Yost H Joseph, Essner Jeffrey J, Sittaramane Vinoth K, Wolman Marc A, Chandrasekhar Anand, Halloran Mary C   +5 more
doaj   +1 more source

Customer satisfaction with career guidance: a literature review [PDF]

, 2015
This paper reports on the findings from a review of the literature relating to customer satisfaction with career guidance services. The review finds that reported levels of satisfaction with career guidance are typically high (ranging between 70-89 ...
Neary, S., Mackay, Susan, Hooley, Tristram, Morris, Marian   +3 more
core   +1 more source

The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance. [PDF]

PLoS Genetics, 2012
The mechanisms linking guidance receptors to cytoskeletal dynamics in the growth cone during axon extension remain mysterious. The Rho-family GTPases Rac and CDC-42 are key regulators of growth cone lamellipodia and filopodia formation, yet little is ...
Rafael S Demarco, Eric C Struckhoff, Erik A Lundquist   +2 more
doaj   +1 more source

Independent signaling by Drosophila insulin receptor for axon guidance and growth

Frontiers in Physiology, 2014
The Drosophila insulin receptor (DInR) regulates a diverse array of biological processes including growth, axon guidance, and sugar homeostasis. Growth regulation by DInR is mediated by Chico, the Drosophila homolog of vertebrate insulin-receptor ...
Caroline Rita Li, Dongyu eGuo, Leslie ePick   +2 more
doaj   +1 more source

Identification of Key Proteins Involved in Axon Guidance Related Disorders: A Systems Biology Approach [PDF]

, 2018
Axon guidance is a crucial process for growth of the central and peripheral nervous systems. In this study, 3 axon guidance related disorders, namely- Duane Retraction Syndrome (DRS) , Horizontal Gaze Palsy with Progressive Scoliosis (HGPPS) and ...
Ishtiaque Ahammad, Ishtiaque Ahammad (4967395), Ishtiaque, Ahammad   +2 more
core   +1 more source

Where does axon guidance lead us? [version 1; referees: 2 approved]

F1000Research, 2017
During neural circuit formation, axons need to navigate to their target cells in a complex, constantly changing environment. Although we most likely have identified most axon guidance cues and their receptors, we still cannot explain the molecular ...
Esther Stoeckli
doaj   +1 more source

Optogenetic axon guidance in embryonic zebrafish

STAR Protocols, 2021
Summary: Axons form the long-range connections of biological neuronal networks, which are built through the developmental process of axon guidance. Here, we describe a protocol to precisely and non-invasively control axonal growth trajectories in live ...
James M. Harris, Andy Yu-Der Wang, Paola Arlotta   +2 more
doaj   +1 more source