Results 101 to 110 of about 1,664,796 (355)

Recent advances in understanding pathophysiology of non-nutritional stunting in very preterm infants [PDF]

open access: yesClinical and Experimental Pediatrics
Very preterm infants (VPIs) often experience extrauterine growth failure. Therefore, aggressive nutritional management of VPIs is recommended with the goal of achieving the postnatal growth of an equivalent fetus.
Eduardo Cuestas, Alina Rizzotti
doaj   +1 more source

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study [PDF]

open access: yes, 2019
Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment.
Allegretti, M.   +7 more
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Nutritional status and access to clean fuels: Evidence from South Asia [PDF]

open access: yes
Indoor air pollution due to solid fuels is among the ten most important risk factors in global burden of disease leading to respiratory diseases, anaemia, blindness and other disorders.
Bhagowalia, Priya, Gupta, Parul
core   +1 more source

GEOGRAPHIC DISTRIBUTION OF TRAINING IN PHYSICAL THERAPY IN BRAZIL: DISORDERED GROWTH AND REGIONAL INEQUALITY

open access: green, 2021
Lydia Chrismann Espíndola Koetz   +2 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Buckling by disordered growth

open access: yesPhysical Review E
Buckling instabilities driven by tissue growth underpin key developmental events such as the folding of the brain. Tissue growth is disordered due to cell-to-cell variability, but the effects of this variability on buckling are unknown. Here, we analyze what is perhaps the simplest setup of this problem: the buckling of an elastic rod with fixed ends ...
Rahul G. Ramachandran   +2 more
openaire   +5 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Developmental trajectories of body mass index and emotional-behavioral functioning of underweight children. A longitudinal study [PDF]

open access: yes, 2016
Although several studies have addressed developmental trajectories from childhood to adolescence of internalizing/externalizing problems, limited attention has been given to underweight children.
Almenara, Carlos A.   +5 more
core   +1 more source

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