Results 81 to 90 of about 894,625 (303)
Autism spectrum disorder (ASD) is a pervasive neurodevelopmental disorder characterized by impaired social interactions and communication, repetitive, or stereotyped behavior.
Boqing Xu +5 more
doaj +1 more source
Objective To investigate the effects of a disintegrin and metalloprotease domain 10 (ADAM10) inhibitor on synaptic structure and blood-brain barrier (BBB) permeability in rats with autism-like behavior.
YANG Jingyuan, LI Xiaoli, WU Chunyan
doaj +1 more source
Isolated Growth Hormone Deficiency
Growth hormone deficiency (GHD) is the most frequent pituitary hormone deficiency in childhood, with an incidence of 1 in 4000–10,000 live births. GHD can be congenital (genetic or due to hypothalamic/pituitary abnormalities) or acquired and can be ...
Lavinia Sanfilippo +3 more
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
An Overview of Immunogenetic in Celiac Disease
Introduction: Celiac disease is an autoimmune disease caused by persistent intolerance to gluten, which is causedin people who are genetically predisposed.
Majid Aflatoonian
doaj
The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley +1 more source
Introduction: The acquisition of speech and language constitutes a dynamic part of two-year-old children s growth. Expressive lexicon is a key indicator of language ability in these children.
Mahmood Bijankhan +5 more
doaj
Special Issue: “X-Linked Hypophosphatemia”
Rickets and osteomalacia are associated with impaired mineralization in growth plate cartilage and the bone osteoid [...
Seiji Fukumoto, Yukihiro Hasegawa
core +1 more source
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Recent advances in understanding pathophysiology of non-nutritional stunting in very preterm infants [PDF]
Very preterm infants (VPIs) often experience extrauterine growth failure. Therefore, aggressive nutritional management of VPIs is recommended with the goal of achieving the postnatal growth of an equivalent fetus.
Eduardo Cuestas, Alina Rizzotti
doaj +1 more source

