Results 61 to 70 of about 7,062,648 (266)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Predicting autism spectrum disorder severity in children based on specific language milestones: a random forest model approach

Child and Adolescent Psychiatry and Mental Health
Background Language impairments are among the most prevalent co-occurring conditions in children with autism spectrum disorder (ASD), and delayed language milestones often serve as early developmental warning signs.
Haiyi Xiong, Xueli Xiang, Xiao Liu, Ting Yang, Jinjin Chen, Jie Chen, Tingyu Li   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Postnatal Growth Patterns and Deviations in Singleton and Twin Infants: A Prospective Cohort Study on Infants Appropriate and Small for Gestational Age

Pediatric Discovery
Small for gestational age (SGA) and twin infants are at increased risk of growth deviations, but postnatal catch‐up growth (CUG) patterns across singleton, twin, appropriate for gestational age (AGA), and SGA groups remain unclear.
Yannan Wan, Ting Pan, Zhanzhan Zhang, Yuanfeng Zhong, Qian Chen, Xuelin Xia, Lin Zhu, Li Chen, Xuan Zhang   +8 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Differences in catch-up growth and its relationship to nutritional status between SGA and AGA twins and singletons in the first year after birth: a prospective cohort study

Scientific Reports
To compare the difference between appropriate for gestational age (AGA) and small for gestational age (SGA) of singleton and twin in terms of catch-up growth (CUG) and nutritional status in the first year after birth through a prospective cohort study. A
Minghui Xiong, Ting Pan, Zhanzhan Zhang, Yuanfeng Zhong, Qian Chen, Yannan Wan, Lin Zhu, Li Chen, Xuan Zhang   +8 more
doaj   +1 more source

Clinical Findings and Dental Manifestations Associated With Microcephalic Osteodysplastic Primordial Dwarfism Type II: A Case Report

Journal of Pediatrics Review, 2022
Background: Microcephalic Osteodysplastic Primordial Dwarfism type 2 (MOPD II) is a rare untreatable genetic disorder characterized by severe prenatal and postnatal growth retardation, microcephaly, bird-headed face (receding forehead and chin, a ...
Bahareh Nazemi Salman, Nazila Biglar, Masoumeh Mirkeshavarz, Ghasem Ansari   +3 more
doaj  

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Cushing’s syndrome and early growth hormone hypersecretion in a child with Carney complex: a case report

Frontiers in Endocrinology
IntroductionCarney complex (CNC) is a rare autosomal dominant syndrome characterized by multiple endocrine and non-endocrine tumors. In childhood, Cushing’s syndrome due to primary pigmented nodular adrenocortical disease (PPNAD) may occur, while growth ...
Gaia Pietropaolo, Adalgisa Festa, Giulio Rivetti, Federica Messa, Giovanni Di Iorio, Antonella Klain, Valeria Pellino, Daniela Cioffi, Rosario Ferrigno, Maria Cristina Savanelli, Emanuele Miraglia Del Giudice, Anna Grandone   +11 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source