Results 41 to 50 of about 7,062,648 (266)

Inhibiting NLRP3 inflammasome signaling pathway promotes neurological recovery following hypoxic-ischemic brain damage by increasing p97-mediated surface GluA1-containing AMPA receptors

open access: yesJournal of Translational Medicine, 2023
Background The nucleotide-binding oligomeric domain (NOD)-like receptor protein 3 (NLRP3) inflammasome is believed to be a key mediator of neuroinflammation and subsequent secondary brain injury induced by ischemic stroke.
Yuxin Chen   +9 more
doaj   +1 more source

Chicken floss and catfish nuggets supplementary to increasing weight gain in stunted children

open access: yesMedisains, 2023
Background: Stunted children are not only less tall, but most of them are also underweight. Lack of nutritional intake, especially protein intake, is suspected as one of the factors.
Krisdiana Wijayanti   +2 more
doaj   +1 more source

Buckling by disordered growth

open access: yesPhysical Review E
Buckling instabilities driven by tissue growth underpin key developmental events such as the folding of the brain. Tissue growth is disordered due to cell-to-cell variability, but the effects of this variability on buckling are unknown. Here, we analyze what is perhaps the simplest setup of this problem: the buckling of an elastic rod with fixed ends ...
Ramachandran, Rahul G.   +2 more
openaire   +5 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Parental Anthropometric Indices and Obesity in Children

open access: yesActa Medica Iranica, 2016
The aim of this study was to investigate the correlation between each parent’s Body Mass Index (BMI) and maternal age with weight status of children. This was an analytic cross-sectional study which was conducted on 12-year-old students from different ...
Shahin Koomanaee   +5 more
doaj  

IMPLEMENTATION OF STUNTING PROGRAM IN INDONESIA: A NARRATIVE REVIEW

open access: yesJurnal Administrasi Kesehatan Indonesia, 2022
Background: Stunting is one of the nutritional problems in the world, especially in Indonesia. Aims: This study aimed to describe the implementation of stunting programs in Indonesia, Related to specific and sensitive nutrition interventions in ...
Siti Zaleha, Haerawati Idris
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Diagnostic Value of IL-6, CRP, WBC, and Absolute Neutrophil Count to Predict Serious Bacterial Infection in Febrile Infants

open access: yesActa Medica Iranica, 2015
Since  clinical  manifestations  of  most  febrile  infants  younger  than  three  months  old  are nonspecific, differentiation of Serious Bacterial Infection (SBI) from self-limiting viral illness is a significant challenge for pediatricians.
Marjaneh Zarkesh   +5 more
doaj  

Effect of resistance and aerobic exercises on bone mineral density, muscle strength and functional ability in children with hemophilia

open access: yesEgyptian Journal of Medical Human Genetics, 2014
Background and purpose: Children with hemophilia are at risk for reduced bone mineral density (BMD), muscle strength and functional ability as a result of reduced leisure-time activity and less involvement in intense activities.
Mohamed A. Eid   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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