Results 111 to 120 of about 1,494,529 (338)

Association of a MET genetic variant with autism-associated maternal autoantibodies to fetal brain proteins and cytokine expression. [PDF]

open access: yes, 2011
The contribution of peripheral immunity to autism spectrum disorders (ASDs) risk is debated and poorly understood. Some mothers of children with ASD have autoantibodies that react to fetal brain proteins, raising the possibility that a subset of ASD ...
Ashwood, P   +4 more
core   +2 more sources

Association Between Basic Immunization Status and Stunting in Toddlers Aged 12-59 Months in Indonesia [PDF]

open access: yesJournal of Preventive Medicine and Public Health
Objectives: Immunization has been identified as a specific nutrition-related intervention to address the direct causes of stunting. This study examines the association between basic immunization status and stunting among toddlers in Indonesia.
Eka Desi Purwanti   +2 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Human Pancreas GH-Releasing Factor Analog Restores High-Amplitude GH Pulses in CNS Lesion-Induced GH Deficiency [PDF]

open access: yes, 1983
Lesions of the ventromedial-arcuate (VMH-ARC) region of the hypothalamus result in impaired growth accompanied by a marked suppression in spontaneous GH secretory bursts. We studied the effects of an analog of the recently characterized human pancreas GH-
Eikelboom, Rudy   +2 more
core   +2 more sources

Time, the final frontier

open access: yesMolecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain   +3 more
wiley   +1 more source

Literature Size Related to Diagnostic Inaccuracy of Personality Disorders [PDF]

open access: yes, 2001
Personality disorders offer clinicians a unique diagnostic challenge. The purpose of this study was to examine the relationship between literature size and diagnostic accuracy for personality disorders.
Intoccia, Vincent
core   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

open access: yesMolecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Modelling postharvest quality behaviour as affected by preharvest conditions [PDF]

open access: yes, 2003
Some hundred years ago, wise men decided that preharvest research and applications had to be regarded separated from the postharvest handling and behaviour. Over the years, both areas developed completely separated.
Heuvelink, E.   +3 more
core   +2 more sources

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