Results 191 to 200 of about 6,896,550 (362)

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Growth factors

, 2018
The growth of eukaryotic cells is modulated by various influences, of which growth factors are amongst the most important for many cell types. A wide range of polypeptide growth factors have been identified .
openaire   +1 more source

CARBON DIOXIDE, COCARBOXYLASE, CITROVORUM FACTOR, AND COENZYME A AS ESSENTIAL GROWTH FACTORS FOR A SAPROPHYTIC TREPONEME (S-69)

, 1954
Harry G. Steinman, Vance I. Oyama, Henry O. Schulze   +2 more
openalex   +1 more source

Regulation of nerve growth factor synthesis [PDF]

, 1989
Bandtlow, C. E., Goetzl, Edward J., Heumann, R., Lindholm, D., Meyer, Michael, Rohrer, H., Thoenen, Hans   +6 more
core  

Depletion of Non-Renewable Resources and Endogenous Technical Change [PDF]

Non-renewable resources are an obstacle for positive long run growth if they are essential for production, households solve an intertemporal Ramsey problem and population is growing.
Juergen Antony
core  

Circulating tumor DNA monitoring and blood tumor mutational burden in patients with metastatic solid tumors treated with atezolizumab

Molecular Oncology, EarlyView.
In patients treated with atezolizumab as a part of the MyPathway (NCT02091141) trial, pre‐treatment ctDNA tumor fraction at high levels was associated with poor outcomes (radiographic response, progression‐free survival, and overall survival) but better sensitivity for blood tumor mutational burden (bTMB).
Charles Swanton, Russell W. Madison, Candice Francheska B. Tambaoan, Funda Meric‐Bernstam, Christopher J. Sweeney, Razelle Kurzrock, Howard A. Burris III, David R. Spigel, Hanna Tukachinsky, Jason Hughes, Julia Malato, Bongin Yoo, Tania Szado, Cheryl Schwab, Lincoln W. Pasquina, Amaya Gasco, Katja Schulze, Claire F. Friedman   +17 more
wiley   +1 more source

Growth Factors

, 2011
Any cell needs extracellular signals for its growth, proliferation, and survival, among other events. Chemical, mechanical, electrical, and other physical interactions of cells with the extracellular matrix yield functional and structural signals for normal cellular activity as well as formation and maintenance of three-dimensional tissues ...
openaire   +1 more source

RELATION OF A GROWTH FACTOR REQUIRED BY LACTOBACILLUS CASEI ε TO THE NUTRITION OF THE CHICK

, 1941
B. L. Hutchings, N. Bohonos, D.M. Hegsted, C. A. Elvehjem, W. H. Peterson   +4 more
openalex   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Protein kinase B inhibitors enhance the sensitivity of translocated promoter region-fibroblast growth factor receptor 1 cells to fibroblast growth factor receptor 1 inhibitor-induced apoptosis. [PDF]

J Int Med Res
Lv M, Shangguan W, Zhao Q, Li Y, Zhao Q, Li F.   +5 more
europepmc   +1 more source