Results 271 to 280 of about 6,799,987 (385)
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
In vitro and in vivo study of concentrated growth factor (CGF) mediating macrophage polarization in bone defect repair. [PDF]
Xin D+6 more
europepmc +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Unidentified Growth Factors Required by Chicks and Poults
Gerald F. Combs+2 more
openalex +1 more source
Nuclear prothymosin α inhibits epithelial‐mesenchymal transition (EMT) in lung cancer by increasing Smad7 acetylation and competing with Smad2 for binding to SNAI1, TWIST1, and ZEB1 promoters. In early‐stage cancer, ProT suppresses TGF‐β‐induced EMT, while its loss in the nucleus in late‐stage cancer leads to enhanced EMT and poor prognosis.
Liyun Chen+12 more
wiley +1 more source
Correction: Biomimetic proteoglycan nanoparticles for growth factor immobilization and delivery.
Zandi N+6 more
europepmc +1 more source
Correction: Exploring the role of epidermal growth factor receptor variant III in meningeal tumors. [PDF]
Rana R+10 more
europepmc +1 more source
Observations on an Unknown Dietary Factor Essential for Human Growth
Selma E. Snyderman+5 more
openalex +1 more source
Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?
Chen‐xi Li, Zhong‐cheng Gong
wiley +1 more source