Evaluation of PTEN Inhibitor Following Spinal Cord Injury on Recovery of Voiding Efficiency and Motor Function Observed by Regeneration in Spinal Cord [PDF]
Purpose Neurogenic bladder (NB) associated with spinal cord injury (SCI) is a serious health problem. However, no effective treatment has been developed for SCI patients with NB.
Young Sam Cho, Su Jin Kim, Khae Hawn Kim
doaj +1 more source
The growth factor of matter perturbations in an f(R) gravity [PDF]
The growth of matter perturbations in the $f(R)$ model proposed by Starobinsky is studied in this paper. Three different parametric forms of the growth index are considered respectively and constraints on the model are obtained at both the $1\sigma$ and $2\sigma$ confidence levels, by using the current observational data for the growth factor.
arxiv +1 more source
Role of growth factors in the pathogenesis of tissue fibrosis in systemic sclerosis. [PDF]
The most severe clinical and pathologic manifestations of systemic sclerosis (SSc) are the result of a fibrotic process characterized by the excessive and often progressive deposition of collagen and other connective tissue macromolecules in skin and ...
Castro, Susan V.+2 more
core +2 more sources
Growth induced instabilities in a circular hyperelastic plate [PDF]
In this work, we have explored growth-induced mechanical instability in an isotropic circular hyperelastic plate. Consistent two-dimensional governing equations for a plate under a general finite strain are derived using a variational approach. The derived plate equations are solved using the compound matrix method for two cases of axisymmetric growth ...
arxiv
Targeting Growth Factor and Cytokine Pathways to Treat Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a chronic interstitial lung disease of unknown origin that usually results in death from secondary respiratory failure within 2–5 years of diagnosis.
Hongbo Ma+7 more
doaj +1 more source
Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey+39 more
core +2 more sources
Blood-derived growth factor preparations have long been employed to improve perfusion and aid tissue repair. Among these, platelet-rich plasma (PRP)-based therapies have seen the widest application, albeit with mixed clinical results to date.
Ektoras Hadjipanayi+15 more
doaj +1 more source
Porcine bone scaffolds adsorb growth factors secreted by MSCs and improve bone tissue repair [PDF]
An ideal tissue-engineered bone graft should have both excellent pro-osteogenesis and pro-angiogenesis properties to rapidly realize the bone regeneration in vivo . To meet this goal, in this work a porcine bone scaffold was successfully used as a Trojan
Bressan, Eriberto+6 more
core +2 more sources
Sequential Delivery of Dual Growth Factors from Injectable Chitosan-Based Composite Hydrogels
Local administration of platelet-derived growth factor-BB (PGDF-BB) and bone morphogenetic protein-2 (BMP-2) in a sequential release manner could substantially promote bone healing.
Qing Min+5 more
doaj +1 more source
Crystal Structure of Imaginal Disc Growth Factor-2 [PDF]
Imaginal disc growth factor-2 (IDGF-2) is a member of a recently described family of Drosophila melanogaster-soluble polypeptide growth factors that promote cell proliferation in imaginal discs.
Llera, Andrea Sabina+3 more
core +1 more source