Results 71 to 80 of about 6,589,084 (383)

Characterization of fungal carbonyl sulfide hydrolase belonging to clade D β‐carbonic anhydrase

FEBS Letters, EarlyView.
Here, we performed a functional analysis of the fungal enzymes belonging to clade D of the β‐class carbonic anhydrase family (β‐D‐CA). The β‐D‐CAs in the basidiomycete Gloeophyllum trabeum and the ascomycete Trichoderma harzianum showed very low activity in the hydration of CO2 but exhibited high activity in the hydrolysis of carbonyl sulfide (COS ...
Ryuka Iizuka, Takahiro Ogawa, Rikako Tsukida, Keiichi Noguchi, David Hibbett, Yoko Katayama, Makoto Yoshida   +6 more
wiley   +1 more source

Advanced Growth Factor Delivery Systems in Wound Management and Skin Regeneration

Molecules, 2017
Growth factors are endogenous signaling molecules that regulate cellular responses required for wound healing processes such as migration, proliferation, and differentiation.
Jin Woo Park, Seung Rim Hwang, In-Soo Yoon   +2 more
doaj   +1 more source

Growth Factors in Regeneration and Regenerative Medicine: “the Cure and the Cause”

Frontiers in Endocrinology, 2020
The potential rapid advance of regenerative medicine was obstructed by findings that stimulation of human body regeneration is a much tougher mission than expected after the first cultures of stem and progenitor cells were established.
Konstantin Yu. Kulebyakin, Konstantin Yu. Kulebyakin, Peter P. Nimiritsky, Peter P. Nimiritsky, Pavel I. Makarevich, Pavel I. Makarevich   +5 more
doaj   +1 more source

An acidic fibroblast growth factor protein generated by alternate splicing acts like an antagonist. [PDF]

, 1992
Polymerase chain reaction amplification of cDNA for acidic fibroblast growth factor in several lines of cultured human cells revealed two forms of mRNA.
Goetzl, EJ, Golden, JA, Kha, H, Migchielsen, AA, Turck, CW, Yu, YL   +5 more
core  

Basic fibroblast growth factor (bFGF) in rodent testis [PDF]

, 1992
We have previously described a 30 kDa basic fibroblast growth factor (bFGF)-like protein in rodent testicular homogenates and have shown that pachytene spermatocytes are the sites of predominant immunoreactivity for this bFGF-like protein (Mayerhofer, A.,
Artur Mayerhofer, Barthels, Beilvé, Bellvé, Braunhut, Claudia Grothe, Djakiew, Facett, Georgia Lahr, Gospodarowicz, Grothe, Grothe, Jaillard, Kaplan, Kimmelman, Klaus Seidl, Kurokawa, Lahr, Maier, Manfred Gratzl, Mayerhofer, Moscatello, Prats, Presta, Sabine Bucher, Sharpe, Skinner, Smith, Storey, Ueno, Volk, Walter Knöchel, Westermann, Wolgemuth   +33 more
core   +1 more source

A histidine‐rich extension of the mitochondrial F0 subunit ATP6 from the ice worm Mesenchytraeus solifugus increases ATP synthase activity in bacteria

FEBS Letters, EarlyView.
The glacier ice worm Mesenchytraeus solifugus survives year‐round at 0 °C. Its ATP6 subunit, which forms a regulatory component of the proton pore in mitochondrial ATP synthase, has a carboxy‐terminal extension not found in any other organism examined to date. Here, we show that fusion of this extension to the homologous AtpB protein in E. coli results
Truman Dunkley, Daniel H. Shain, Eric A. Klein   +2 more
wiley   +1 more source

Thick collagen-based 3D matrices including growth factors to induce neurite outgrowth [PDF]

Acta Biomaterialia 8, 9 (2012) 3302-3312, 2012
Designing synthetic microenvironments for cellular investigations is a very active area of research at the crossroads of cell biology and materials science. The present work describes the design and functionalization of a three-dimensional (3D) culture support dedicated to the study of neurite outgrowth from neural cells.
arxiv   +1 more source

Lysosomal Regulation of mTORC1 by Amino Acids in Mammalian Cells

Biomolecules, 2017
The mechanistic target of rapamycin complex 1 (mTORC1) is a master regulator of cell growth in eukaryotic cells. The active mTORC1 promotes cellular anabolic processes including protein, pyrimidine, and lipid biosynthesis, and inhibits catabolic ...
Yao Yao, Edith Jones, Ken Inoki
doaj   +1 more source

Growth Factor Regulation of Growth Factors in Articular Chondrocytes [PDF]

Journal of Biological Chemistry, 2009
Several lines of evidence indicate that polypeptide growth factors are important in articular cartilage homeostasis and repair. It is not yet clear how these growth factors are regulated. We tested the hypothesis that the growth factors responsible for regulating cartilage are themselves regulated by growth factors.
George J. Eckert, Shuiliang Shi, Stephen B. Trippel, Scott Mercer   +3 more
openaire   +3 more sources

Elucidation of interface interactions between a dehydratase domain and an acyl carrier protein in cremimycin polyketide synthase

FEBS Letters, EarlyView.
In modular polyketide synthases, the dehydratase (DH) domain catalyzes the dehydration reaction of the β‐hydroxyacyl unit attached to the cognate acyl carrier protein (ACP) domain. However, it is unclear how DH interacts with ACP during the reaction. In this study, we identified DH–ACP interface residues, providing the first detailed insights into DH ...
Kaede Kotagiri, Haruka Tachibana, Daisuke Kawasaki, Taichi Chisuga, Toma Kashima, Shinya Fushinobu, Fumitaka Kudo, Tadashi Eguchi, Akimasa Miyanaga   +8 more
wiley   +1 more source