Results 71 to 80 of about 7,029,797 (363)

Growth factor releasing scaffolds for cartilage tissue engineering [PDF]

open access: yes, 2006
Over the last century, life expectancy has increased at a rapid pace resulting in an increase of articular cartilage disorders. To solve this problem, extensive research is currently performed using tissue engineering approaches.
Sohier, Jerome
core   +2 more sources

Functional Profiling of Transcription Factor Genes in Neurospora crassa. [PDF]

open access: yes, 2017
Regulation of gene expression by DNA-binding transcription factors is essential for proper control of growth and development in all organisms. In this study, we annotate and characterize growth and developmental phenotypes for transcription factor genes ...
Bekman, Thomas   +17 more
core   +1 more source

Goodbye flat lymphoma biology

open access: yesFEBS Letters, EarlyView.
Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria   +3 more
wiley   +1 more source

Growth Factors in the Nucleolus? [PDF]

open access: yesThe Journal of Cell Biology, 1998
In eukaryotic cells containing tandem repeated ribosomal RNA genes, there appears a specialized region of chromatin, carrying out gene transcription, rRNA processing, and nascent ribosomal subunit assembly—the nucleolus.
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Growth factor for influenza bacteria

open access: yesCalifornia Agriculture, 1961
California Agriculture - All ...
California Agriculture
doaj  

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

open access: yesFEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li   +3 more
wiley   +1 more source

Growth factors in glomerulonephritis

open access: yesKidney International, 1993
A 63-year-old white male was admitted to the hospital because of renal insufficiency. He recently had been treated at another hospital for bleeding peptic ulcer disease. He had had two or three episodes of gross hematuria dating back to approximately 10 years prior to admission and had had a gradual decline in renal function over the previous 3 years ...
openaire   +3 more sources

Assessing the Real-Time Informational Content of Macroeconomic Data Releases for Now-/Forecasting GDP: Evidence for Switzerland [PDF]

open access: yes, 2012
This study utilizes the dynamic factor model of Giannone et al. (2008) in order to make now-/forecasts of GDP quarter-on-quarter growth rates in Switzerland. It also assesses the informational content of macroeconomic data releases for forecasting of the
Chapman, Ann-Marie   +4 more
core   +5 more sources

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

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