Results 1 to 10 of about 2,009,855 (385)

Impact of sustained transforming growth factor-β receptor inhibition on chromatin accessibility and gene expression in cultured human endometrial MSC [PDF]

, 2020
Endometrial mesenchymal stem cells (eMSC) drive the extraordinary regenerative capacity of the human endometrium. Clinical application of eMSC for therapeutic purposes is hampered by spontaneous differentiation and cellular senescence upon large-scale ...
Brosens, Jan J., Darzi, Saeedeh, Filby, Caitlin, Gargett, Caroline E., Gurung, Shanti, Lucciola, Raffaella, Muter, Joanne, Ott, Sascha, Vrljicak, Pavle   +8 more
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Epidermal growth factor receptor (EGFR) gene alteration and protein overexpression in Malaysian triple-negative breast cancer (TNBC) cohort [PDF]

, 2019
Background: Epidermal growth factor receptor (EGFR) is a member of the ErbB family of tyrosine kinase receptor proteins that plays important roles in tumour cell survival and proliferation.
Abdul Raub, Sayyidi Hamzi, Azhari, Azlah Kamilah, Eswaran, Jeyanthy, Soundararajan, Meera, Syed Husain, Sharifah Noor Akmal, Wan Hasan, Wan Atiqah Najiah, Zakaria, Zubaidah, Zulkifle, Muhamad Farid   +7 more
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Inhibiting epidermal growth factor receptor at a distance. [PDF]

, 2014
The epidermal growth factor receptor (EGFR) tyrosine kinase is implicated in a large number of human cancers. Most EGFR inhibitors target the extracellular, growth factor-binding domain or the intracellular, ATP-binding domain. Here we describe molecules
Denton, Elizabeth, Schepartz, Alanna, Sinclair, Julie   +2 more
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Targeting the EGFR in ovarian cancer with the tyrosine kinase inhibitor ZD1839 (“Iressa”). [PDF]

, 2002
The modulating effects of the orally active epidermal growth factor receptor-specific tyrosine kinase inhibitor ZD 1839 (‘Iressa’) on cell growth and signalling were evaluated in four ovarian cancer cell lines (PE01, PE04, SKOV-3, OVCAR-5) that express ...
A Berchuck, A Levitzki, A Ritchie, AE Wakeling, AJ Crew, BJB Simpson, BJB Simpson, BS Verbeek, D Ferry, DW Fry, F Ciardiello, FM Sirotnak, G Carpenter, J Baselga, J F Smyth, J M Sewell, J Mendelsohn, JMS Bartlett, JR Woodburn, K G Macleod, K Morishige, K Stromberg, MA Olayioye, MP Ezekial, MW Kunkel, P Chen, S P Langdon, SE Egan, SP Langdon, WS Chen   +29 more
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EphA2 is a functional receptor for the growth factor progranulin. [PDF]

, 2016
Although the growth factor progranulin was discovered more than two decades ago, the functional receptor remains elusive. Here, we discovered that EphA2, a member of the large family of Ephrin receptor tyrosine kinases, is a functional signaling receptor
Ahmed, Al-Ayadhi, Andrea Morrione, Atul Goyal, Baker, Bateman, Bhandari, Bhandari, Bogan, Brantley, Brantley-Sieders, Brantley-Sieders, Brantley-Sieders, Brantley-Sieders, Buraschi, Carrasquillo, Catherine Sharpe, Cenik, Chan, Chen, Cheng, Cruts, Cruts, Culouscou, Dave, Dunn, Duxbury, Elizabeth Natkanski, Farach-Carson, Ferluga, Gass, Ghidoni, Gijselinck, Giorgio, Goldoni, Gonzalez, Grindel, He, He, Hess, Hu, Huang, Iozzo, Iozzo, Jun, Kessenbrock, Kohlschütter, Kullander, Lema Tomé, Lemmon, Liliana Schaefer, Lord, Lord, Lovat, Margaryan, Matsubara, Merline, Miao, Minami, Misaki, Monami, Monami, Noberini, Nykjaer, Ogawa, Park, Parri, Petty, Prudencio, Renato V. Iozzo, Romanello, Serrero, Simone Buraschi, Sleegers, Smith, Song, Taddei, Tang, Tangkeangsirisin, Tanimoto, Tanimoto, Thomas Neill, Toh, Toh, Tolkatchev, Van Damme, Van Kampen, Wang, Wesa, Whitelock, Wienken, Wilusz, Wykosky, Wykosky, Xia, Xu, Xu, Yamaguchi, Yang, Zanocco-Marani, Zinchuk, Zoeller   +101 more
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Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer [PDF]

, 2016
The high affinity nerve growth factor (NGF) NGF receptor, p75NTR, is a member of the tumor necrosis factor (TNF) receptor superfamily that shares a conserved intracellular death domain capable of inducing apoptosis and suppressing growth in prostate ...
Biordi, Leda, Colapietro, Alessandro, Festuccia, Claudio, Ficorella, Corrado, Gravina, Giovanni Luca, Jitariuc, Ana, Mancini, Andrea, Marampon, Francesco, Sanità, Patrizia, Scarsella, Luca   +9 more
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Anti epidermal growth factor receptor therapy in small bowel adenocarcinoma [PDF]

, 2018
Rationale:Small bowel adenocarcinoma (SBA) is an uncommon gastrointestinal cancer, thus limited data about treatment for advanced disease are available.
Anselmi, Elisabetta, Falcone, Rosa, Filetti, Marco, Marchetti, Paolo, Roberto, Michela   +4 more
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Fibroblast growth factor/fibroblast growth factor receptor system in angiogenesis. [PDF]

, 2005
Fibroblast growth factors (FGFs) are a family of heparin-binding growth factors. FGFs exert their pro-angiogenic activity by interacting with various endothelial cell surface receptors, including tyrosine kinase receptors, heparan-sulfate proteoglycans ...
Aigner, Arany, Asplin, Auguste, Baird, Baird, Barleon, Bastaki, Bergonzoni, Bikfalvi, Birkle, Blotnick, Bornstein, Bossard, Bottazzi, Breviario, Brown, Brustle, Cao, Cao, Carmeliet, Carmeliet, Carmeliet, Castellon, Chadderton, Chang, Chang, Chang, Chi, Collo, Coltrini, Colvin, Comerota, Compagni, Conforti, Connolly, Costa, Cozzolino, Cross, Czubayko, Daviet, Davis, De Marchis, Dell’Era, Dell’Era, Dell’Era, Deng, Dennis, Desbaillets, Dirix, Eliceiri, Ensoli, Eriksson, Ferrara, Ferrara, Florkiewicz, Folkman, Folkman, Folkman, Freedman, Fulgham, Gabler, Gajdusek, Gajdusek, Garlanda, Gerritsen, Giavazzi, Giavazzi, Gillis, Giordano, Gleich, Gloe, Gonzalez, Griffioen, Grines, Gross, Gualandris, Gualandris, Hanahan, Hanneken, Hanneken, Hartnett, Henke, Herbert, Hiraoka, Ho, Hollingsworth, Hori, Hoying, Hsia, Iozzo, Itoh, Jaakkola, Javerzat, Jih, Kage, Kanda, Kanda, Kandel, Kaneko, Kasahara, Kazemi, Kitayama, Kiuru-Kuhlefelt, Klein, Konerding, Konkle, Koochekpour, Kumar, Kumar, Kumar, Kurz, Kuwabara, Laham, Landgren, Latini, Lazarous, Leali, Lederman, Lee, Lee, Li, Li, Lindahl, Liotta, Lopez, Lozano, Maciag, Magnusson, Mantovani, Margosio, Mathew, Matsumoto, Mattila, McCarthy, McCrohan, Mignatti, Mignatti, Miller, Mongiat, Montesano, Montesano, Morbidelli, Moscatelli, Nachman, Nguyen, Nico, Nicosia, Nurcombe, Ozaki, Padro, Parsons-Wingerter, Partridge, Passaniti, Pellegrini, Pendurthi, Peoples, Pepper, Pepper, Pepper, Perollet, Placanica, Polnaszek, Poole, Poon, Post, Presta, Presta, Presta, Presta, Presta, Presta, Pugh, Quarto, Rak, Reuss, Ria, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Ribatti, Rissanen, Rousseau, Ruegg, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Rusnati, Russo, Sahni, Sahni, Sahni, Sahni, Salgado, Salmivirta, Salustri, Schnaper, Schnaper, Seghezzi, Sellke, Senn, Sepp, Shaw, Sheibani, Shing, Shono, Shono, Simons, Simons, Singh, Souttou, Stokes, Syed, Tabata, Takahashi, Takei, Talarico, Tanghetti, Taraboletti, Taraboletti, Tassi, Taverna, Terranova, Tiefenbacher, Tille, Tobe, Tomanek, Ueno, Underwood, Unger, Vacca, Vlodavsky, Walford, Wang, Wang, Weidner, Weinstein, Wempe, Xu, Xue, Yamaguchi, Yamayoshi, Yoon, Zhang, Zhang, Zhao, Zhou, Zhou, Ziche, Ziche   +253 more
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Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

, 2007
BACKGROUND: Prostaglandin E(2) (PGE(2)) has been shown to modulate angiogenesis and tumour progression via the E-series prostanoid-2 (EP2) receptor. Endometrial adenocarcinomas may be exposed to endogenous PGE(2) and exogenous PGE(2), present at high ...
A.R. Williams, Abramovitz, Benard, Bendvold, Billottet, Buchanan, Davidson, Ferrandina, Giavazzi, Gupta, H.N. Jabbour, Hwang, Jaaro, Jabbour, Jabbour, Jabbour, Jeremias, K.J. Sales, Kitamura, Lumsden, Luttrell, Milling, Narumiya, Pai, Pecorelli, Perchick, Pierce, Presta, R.A. Anderson, Regan, Robertson, S. Battersby, S. Gardner, Sales, Sales, Sales, Sales, Sales, Seger, Smalley, Smith, Taylor, Templeton, Tjandrawinata, Tong, Tsujii, Vane, Woodward, Yoshida   +48 more
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Intraocular Metastases Secondary to Breast Carcinoma Correlates With Upregulation of Estrogen and Progesterone Receptor Expression in the Primary Tumor [PDF]

, 2016
To compare estrogen (ER), progesterone (PR), and human epidermal growth factor-2 (HER2) receptor expression in the primary tumor of patients affected by choroidal metastases from breast carcinoma (BC) versus those with extraocular ...
Frizziero, Luisa, Midena, Edoardo, Miglionico, Giacomo, Parrozzani, Raffaele, Perrini, Pierdavide, Pilotto, Elisabetta, Pulze, Serena, Testi, Ilaria   +7 more
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