Results 1 to 10 of about 2,000,472 (360)
Oncology Reviews, 2023 This work presents the history of the recognition of principal regulatory capacities of estrogen hormones having been mistakenly regarded as breast cancer promoting agents for more than 120 years.
Zsuzsanna Suba
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GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. [PDF]
, 2016 Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous.
David James, C +11 more
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SAGE Open Medical Case Reports, 2023 A 71-year-old non-smoker woman was admitted to our hospital because of left front chest pain. A computed tomography scan showed a large mass of >7.0 cm in the lower left part of the lung and multiple organ metastases in the liver, brain, bone, and left ...
Sosuke Matsumura +7 more
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Maternal hepatic growth response to pregnancy in the mouse [PDF]
, 2011 Pregnancy is characterized by physiological adjustments in the maternal compartment. In this investigation, the influence of pregnancy on maternal liver was examined in CD-1 mice.
Bao, Qi +6 more
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Treatment of pancreatic cancer with epidermal growth factor receptor-targeted therapy
Biologics: Targets & Therapy, 2009 Bryan A Faller, Barbara BurtnessDepartment of Medical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USAAbstract: Pancreatic adenocarcinoma is a common malignancy that remains refractory to available therapies.
Bryan A Faller, Barbara Burtness
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Frontiers in EndocrinologyReceptor tyrosine kinases (RTKs) mediate the actions of growth factors in metazoans. In decapod crustaceans, RTKs are implicated in various physiological processes, such molting and growth, limb regeneration, reproduction and sexual differentiation, and ...
Kaylie A. Flores +4 more
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Pleiotropy as the Mechanism for Evolving Novelty: Same Signal, Different Result
Biology, 2015 In contrast to the probabilistic way of thinking about pleiotropy as the random expression of a single gene that generates two or more distinct phenotypic traits, it is actually a deterministic consequence of the evolution of complex physiology from the ...
John S. Torday
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Neural Regeneration Research, 2022 Numerous molecular mechanisms are being examined in an attempt to discover disease-modifying drugs to slow down the underlying neurodegeneration in Alzheimer’s disease.
Heba M Mansour +3 more
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Increased expression and activity of p75NTR are crucial events in azacitidine-induced cell death in prostate cancer [PDF]
, 2016 The high affinity nerve growth factor (NGF) NGF receptor, p75NTR, is a member of the tumor necrosis factor (TNF) receptor superfamily that shares a conserved intracellular death domain capable of inducing apoptosis and suppressing growth in prostate ...
Biordi, Leda +9 more
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International Journal of Women's Health, 2014 Nathan WD Lamond, Tallal YounisDepartment of Medicine, Dalhousie University at the Queen Elizabeth II Health Sciences Centre, Halifax, NS, CanadaAbstract: In the absence of specific therapy, the 15%–20% of breast cancers demonstrating human ...
Lamond NW, Younis T
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