Results 161 to 170 of about 2,009,855 (385)

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Pseudomonas exotoxin-anti-TAC. Cell-specific immunotoxin active against cells expressing the human T cell growth factor receptor. [PDF]

, 1984
David J. FitzGerald, Thomas A. Waldmann, Mark C. Willingham, Ira Pastan   +3 more
openalex   +1 more source

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Transmembrane signalling at epidermal growth factor receptors overexpressed in NIH 3T3 cells. Phosphoinositide hydrolysis, cytosolic Ca2+ increase and alkalinization correlate with epidermal-growth-factor-induced cell proliferation [PDF]

, 1988
Atanasio Pandiella, Laura Beguinot, Thierry Velu, Jacopo Meldolesi   +3 more
openalex   +1 more source

Inhibition of acyl‐CoA synthetase long‐chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction

Molecular Oncology, EarlyView.
Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, Michelle Karam, Christian Potts, Princess Rodriguez, Ya‐Wei Qiang, Habib Hamidi, Xiangnan Guan, Calvin P. H. Vary, Michaela R. Reagan   +12 more
wiley   +1 more source

Structure and expression of the chicken epidermal growth factor receptor gene locus [PDF]

, 1986
Birgitta Olofsson, Véronique Pizon, Ahmed Zahraoui, A Tavitian, Amu Therwath   +4 more
openalex   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Surgical significance and efficacy of epidermal growth factor receptor tyrosine kinase inhibitors in patients with primary lung adenosquamous carcinoma

Cancer Management and Research, 2018
Chao Zhang,1,* Haitang Yang,2–4,* Baoping Lang,1 Xiangdong Yu,1 Peng Xiao,1 Dian Zhang,1 Liwen Fan,5 Xiao Zhang1 1Department of Thoracic Surgery, The Affiliated Luoyang Central Hospital of Zhengzhou University, Luoyang, China; 2Division of General ...
Zhang C, Yang H, Lang B, Yu X, Xiao P, Zhang D, Fan L, Zhang X   +7 more
doaj  

Elucidating the mechanism of corneal epithelial cell repair: unraveling the impact of growth factors

Frontiers in Medicine
The repair mechanism for corneal epithelial cell injuries encompasses migration, proliferation, and differentiation of corneal epithelial cells, and extracellular matrix remodeling of the stromal structural integrity.
Jinjin Gong, Jinjin Gong, Gang Ding, Zhongkai Hao, Zhongkai Hao, Yuchun Li, Aijun Deng, Chenming Zhang, Chenming Zhang   +8 more
doaj   +1 more source

Sequence of MET protooncogene cDNA has features characteristic of the tyrosine kinase family of growth-factor receptors. [PDF]

, 1987
M Park, Michael Dean, Karen L. Kaul, Michael J. Braun, M A Gonda, G Vande Woude   +5 more
openalex   +1 more source