Results 201 to 210 of about 2,000,472 (360)

Epidermal growth factor receptor (EGFR) downstream signalling pathway in primary colorectal tumours and related metastatic sites: optimising EGFR-targeted treatment options [PDF]

, 2007
Mario Scartozzi, Italo Bearzi, Rossana Berardi, Alessandra Mandolesi, Chiara Pierantoni, Stefano Cascinu   +5 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

The amphiregulin- epidermal growth factor receptor axis as a therapeutic target in sepsis. [PDF]

Front Immunol
Walsh R, Snow TAC, Martinez AZ, Brealey D, Singer M, Das A, Arulkumaran N, University College London Hospitals Critical Care Research Team.   +7 more
europepmc   +1 more source

A computational investigation of deleterious non-synonymous SNPs of epidermal growth factor receptor

, 2011
Dhwani Raghav, Vinay Sharma, Subhash Mohan Agarwal   +2 more
openalex   +1 more source

Association of phosphatase and tensin homolog low and phosphatidylinositol 3-kinase catalytic subunit alpha gene mutations on outcome in human epidermal growth factor receptor 2-positive metastatic breast cancer patients treated with first-line lapatinib plus paclitaxel or paclitaxel alone [PDF]

, 2014
Binghe Xu, Zhongzhen Guan, Zhenzhou Shen, Zhongshen Tong, Zefei Jiang, Junlan Yang, Michelle DeSilvio, Mark W. Russo, Meggan Leigh, Catherine Ellis   +9 more
openalex   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Epidermal growth factor receptor is an essential component in E-cadherin force transduction complexes. [PDF]

J Cell Sci
Zou Y, Allen N, Rauf E, Leckband D.
europepmc   +1 more source

Expression of epidermal growth factor receptor in experimental hamster tongue carcinogenesis.

, 1995
Hatsuhiko Maeda, Hironori Tanaka, Seiichi Konishi, Naohiro Ito, Masayuki Yokoyama, Emiko Sato, Yoichiro Kameyama   +6 more
openalex   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Multimodal ultrasonography for predicting epidermal growth factor receptor mutation in subpleural non-small cell lung carcinoma. [PDF]

Front Oncol
Bai J, Zhang Q, Wang S, Wang H, Yan K, Zhou W, Dong L, Yang W.   +7 more
europepmc   +1 more source