Results 321 to 330 of about 2,000,472 (360)
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Receptors for Nerve Growth Factor
1993Publisher Summary This chapter discusses the two receptors for nerve growth factor (NGF)—namely, (1) the low-affinity NGF receptor and (2) the product of the proto-oncogene trk . It also reviews the way they were originally identified and the structural and functional features of the two receptors.
M V, Chao, D S, Battleman, M, Benedetti
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Growth Factors, Growth-Factor Receptors and Oncogenes
Bio/Technology, 1985In this review we summarize the current knowledge of polypeptide growth factors, their receptors and oncogenes. Recent studies indicate that oncogenes are linked to growth factors and to growth factor receptors, suggesting that these molecules participate in the proliferation of normal and neoplastic cells.
R. M. Kris +3 more
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Epidermal Growth Factor, Epidermal Growth Factor Receptors, Intestinal Growth, and Adaptation
Journal of Parenteral and Enteral Nutrition, 1999Epidermal growth factor (EGF) is an important constituent of several gastrointestinal secretions. Many studies in both animals and humans have shown EGF to have multiple effects upon gut epithelial cells. These include cytoprotection, stimulatory effects on cell proliferation and migration, induction of gene expression such as mucosal enzymes and ...
W M, Wong, N A, Wright
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Growth factor receptors and medulloblastoma
Journal of Neuro-Oncology, 1996Growth factors and their receptors play important roles in the regulation of cell division, development and differentiation. Neurotrophins are growth factors which have not been shown, until recently, to be associated with human neoplasia. Medulloblastoma is a central nervous system tumor which is thought to arise from the external granule cell layer ...
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Growth factors, receptors and cancer
BioEssays, 1986AbstractIt now appears that the molecular events associated with the mitogenic action of growth factors are also the events perturbed in neoplastic lesions. This review outlines the relevance of our recent progress in the biochemistry of growth factors and their receptors to the induction and maintenance of the neoplastic state.
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Epidermal growth factor receptor ≠ nerve growth factor
Neurobiology of Aging, 1989I am perplexed by the authors' complete lack of definition of neurotrophic factors. The agents Butcher and Woolf want to blame are neurite promoting factors, not neurotrophic factors. Treatment of Alzheimer's disease with NGF antagonists might instead exacerbate the death of both basal forebrain neurons and their cortical target neurons, accelerating ...
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Growth factor and growth factor receptor in radiation carcinogenesis
Radiation and Environmental Biophysics, 1991link_to_subscribed_fulltext
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Growth Factor Receptors: The Epidermal Growth Factor Receptor as a Model
1990Secreted polypeptide growth factors such as insulin, insulinlike growth factor I (IGF-I), epidermal growth factor (EGF), platelet-derived growth factor (PDGF), and colony-stimulating factor (CSF-1) initiate complex cytoplasmic and nuclear events. These distinct cellular responses can be attributed to the interaction of hormones with their respective ...
K. C. Oberg, A. Brown, G. Carpenter
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Pancreatic Cancer: Growth Factors and Growth Factor Receptors
1999Cancer of the pancreas presently has an incidence of approximately 8 to 10 cases per 100 000 citizens in industrialised European countries (1), an incidence that has been increasing over the past decades (2,3). In the USA the disease presently represents the fourth leading cause of cancer death in men and in women (1,4,5). Approximately 30 000 patients
H. Friess +5 more
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Epidermal growth factor receptors
European Respiratory Journal, 1989D, Veale, G J, Gibson
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