Oncogenic Signalling of Growth Factor Receptors in Cancer: Mechanisms and Therapeutic Opportunities. [PDF]
Int J Mol Sci, 2022 Dricu A.
europepmc +1 more source
Molecular Oncology, EarlyView.This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian +10 more
wiley +1 more source
Expression of interleukin 2 receptors on activated human B cells. [PDF]
, 1984 Using anti-Tac, a monoclonal anti-interleukin 2 (IL-2) receptor antibody, we have explored the possibility that certain activated B cells display receptors for IL-2.
Bongiovanni, KF +8 more
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Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer. [PDF]
Front Oncol, 2023 Popiel D +21 more
europepmc +1 more source
Supplementary Data from The Green Tea Polyphenol EGCG Potentiates the Antiproliferative Activity of c-Met and Epidermal Growth Factor Receptor Inhibitors in Non–small Cell Lung Cancer Cells [PDF]
, 2023 Shawn A. Milligan +7 more
openalex +1 more source
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Prostaglandin E2 amplifies epidermal growth factor-induced phosphorylation of extracellular signal-regulated kinase (ERK) in hepatocytes [PDF]
, 2006 The signalling pathways of G-protein coupled receptors (GPCRs) and epidermal growth factor receptors (EGFRs) have been shown to communicate in mitogenic processes in many cells.
Lilleby, Peggy
core
Targeting fibroblast growth factor receptors causes severe craniofacial malformations in zebrafish larvae. [PDF]
PeerJ, 2022 Gebuijs L +5 more
europepmc +1 more source
Insulin and Insulin-like Growth Factor I Receptors Utilize Different G Protein Signaling Components [PDF]
, 2001 Stéphane Dalle +4 more
openalex +1 more source
Emerging role of ARHGAP29 in melanoma cell phenotype switching
Molecular Oncology, EarlyView.This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster +3 more
wiley +1 more source