Results 221 to 230 of about 1,257,265 (356)

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Regulation of epithelial growth factor receptors by the oncoprotein E5 during the HPV16 differentiation-dependent life cycle. [PDF]

Tumour Virus Res
Molina MA, Biswas S, Jiménez-Vázquez O, Bodily JM.   +3 more
europepmc   +1 more source

Fibroblast Growth Factor Receptor Family Gene [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Structure Activity Relationships of Quinoxalin-2-one Derivatives as Platelet-Derived Growth Factor-.BETA. Receptor (PDGF.BETA. R) Inhibitors, Derived from Molecular Modeling

, 2008
Yoshikazu Mori, Takatsugu Hirokawa, Katsuyuki Aoki, Hisanori Satomi, Shuichi Takeda, Masaki Aburada, Ken‐ichi Miyamoto   +6 more
openalex   +2 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Targeted Delivery of Rapamycin via Epidermal Growth Factor Receptors in Pancreatic Cancer Cells Inhibits Cell Proliferation and Induces Apoptosis. [PDF]

ACS Omega
Oluremi AS, Baldwin C, Gustavison N, Bashiru M, Oyebade A, Siraj N, Rao RR, Ali N.   +7 more
europepmc   +1 more source

Inhibition of Vascular Endothelial Growth Factor Receptors 1 and 2 Attenuates Natural Killer Cell and Innate Immune Responses in an Experimental Model for Obliterative Bronchiolitis. [PDF]

Am J Pathol, 2022
Krebs R, Tikkanen JM, Raissadati A, Hollmén M, Dhaygude K, Lemström KB.   +5 more
europepmc   +1 more source

A computational investigation of deleterious non-synonymous SNPs of epidermal growth factor receptor

, 2011
Dhwani Raghav, Vinay Sharma, Subhash Mohan Agarwal   +2 more
openalex   +1 more source

Epidermal growth factor (EGF) stimulates association and kinase activity of Raf-1 with the EGF receptor.

, 1991
Harald App, Ronen Hazan, Asher Zilberstein, Axel Ullrich, Joseph Schlessinger, U R Rapp   +5 more
openalex   +2 more sources