Results 241 to 250 of about 1,257,265 (356)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Synthesis, Radiolabeling, and Biodistribution Study of a Novel DOTA-Peptide for Targeting Vascular Endothelial Growth Factor Receptors in the Molecular Imaging of Breast Cancer. [PDF]

Pharmaceutics
Ebrahimi F, Zargari NR, Akhlaghi M, Asghari SM, Abdi K, Balalaie S, Asadi M, Beiki D.   +7 more
europepmc   +1 more source

Airway Epithelial Dysfunction in Asthma: Relevant to Epidermal Growth Factor Receptors and Airway Epithelial Cells. [PDF]

J Clin Med, 2020
Inoue H, Akimoto K, Homma T, Tanaka A, Sagara H.   +4 more
europepmc   +1 more source

Sequential therapy with bevacizumab and epidermal growth factor receptor-directed agents for metastatic colorectal carcinoma: A retrospective, registry-based analysis [PDF]

, 2017
Tomáš Büchler, Renata Chloupková, Alexandr Poprach, Ondřej Fiala, Igor Kišš, Kateřina Kopečková, Ladislav Dušek, Lubomír Slavíček, M Kohoutek, Jindřich Fínek, Marek Svoboda, Luboš Petruželka, Bohuslav Melichar   +12 more
openalex   +1 more source

Data from Epidermal Growth Factor Receptor Tyrosine Phosphorylation and Signaling Controlled by a Nuclear Receptor Coactivator, Amplified in Breast Cancer 1

, 2023
Tyler Lahusen, Mark Fereshteh, Annabell S. Oh, Anton Wellstein, Anna T. Riegel   +4 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Expression of epidermal growth factor receptor in experimental hamster tongue carcinogenesis.

, 1995
Hatsuhiko Maeda, Hironori Tanaka, Seiichi Konishi, Naohiro Ito, Masayuki Yokoyama, Emiko Sato, Yoichiro Kameyama   +6 more
openalex   +1 more source

Effect of Insulin and Losartan on Modulation of Insulin-Like Growth Factor 1 Receptor at Heart Level in Diabetic Rats [PDF]

, 2007
Anwar B. Bikhazi, Wael Maharsy, Lina N. Kadi, Nahla Issa, Ghinwa M. Barakat, Nuha Nuwayri‐Salti, George K. Karam, Omar Batal, Khalil M. Bitar   +8 more
openalex   +1 more source

Data from Enhanced Hepatocyte Growth Factor Signaling by Type II Transforming Growth Factor-β Receptor Knockout Fibroblasts Promotes Mammary Tumorigenesis

, 2023
Nikki Cheng, Anna Chytil, Yu Shyr, Alison Joly, Harold L. Moses   +4 more
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source