Results 81 to 90 of about 1,257,265 (356)
Aktuelle Entwicklungen und Perspektiven zielgerichteter Therapien [PDF]
, 2010 Current Developments and Perspectives in Targeted Therapies Many different approaches for improving the prognosis of patients with advanced non-small-cell lung cancer (NSCLC) are currently being investigated.
Dickgreber, Nicolas +6 more
core +1 more source
Tumor Biology, 2017 The use of trastuzumab in patients with breast cancer that overexpresses human epidermal growth factor receptor 2 has significantly improved treatment outcomes.
Marianne Nordlund Broughton +6 more
doaj +1 more source
Supplementary Figure 6 from Sulindac Metabolites Induce Proteosomal and Lysosomal Degradation of the Epidermal Growth Factor Receptor [PDF]
, 2023 Heather A. Pangburn +2 more
openalex +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
TGF beta type II receptor signaling controls Schwann cell death and proliferation in developing nerves [PDF]
, 2006 During development, Schwann cell numbers are precisely adjusted to match the number of axons. It is essentially unknown which growth factors or receptors carry out this important control in vivo.
D'Antonio, M +6 more
core
Growth factors and experimental arterial grafts [PDF]
, 2016 Background: The production of growth factors from several experimental arterial conduits was determined. Methods: We implanted 105 experimental arterial grafts that were 1 cm long in the abdominal aorta of Lewis rats (average weight, 250 g).
BORRELLI, Valeria +6 more
core +1 more source
From Tumor to Bone: Growth Factor Receptors as Key Players in Cancer Metastasis
Frontiers in Bioscience-LandmarkThis review article explores the intricate correlation between growth factors and bone metastases, which play a crucial role in the development of several types of malignancies, namely breast, prostate, lung, and renal cancers.
Khalid Said Mohammad +1 more
doaj +1 more source
The beneficial effect of suramin on monocrotaline-induced pulmonary hypertension in rats. [PDF]
PLoS ONE, 2013 BACKGROUND:Pulmonary hypertension (PH) is a progressive disorder characterized by an increase in pulmonary artery pressure and structural changes in the pulmonary vasculature.
Mohamed Izikki +11 more
doaj +1 more source
Insulin-Like Growth Factor Receptor [PDF]
Journal of Thoracic Oncology, 2011 The insulin-like growth factor (IGF) signaling axis plays an essential role in the balance between cellular proliferation and apoptosis. Higher levels of IGF receptor are seen in lung tumor cells than normal tissue. IGF-1 receptor (IGFR-1R) and its ligand IGF-2 is overexpressed in non-small cell lung cancer (NSCLC).
openaire +2 more sources
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source