Results 201 to 210 of about 6,173,170 (321)

Beyond insulin-like growth factor-1 (IGF-1) normalization: portal insulin and hepatic growth hormone (GH) sensitivity across metabolic disease. [PDF]

Arch Endocrinol Metab
van AJ, Neggers SJ, Kopchick JJ, Boguszewski CL.   +3 more
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Current Insights into the Role of the Growth Hormone-Insulin-Like Growth Factor System in Short Children Born Small for Gestational Age.

Horm Res Paediatr, 2019
Renes JS, van Doorn J, Hokken-Koelega ACS.   +2 more
europepmc   +1 more source

New insights into epileptic spasm generation and treatment from the TTX animal model

Epilepsia Open, EarlyView.
Abstract Currently, we have an incomplete understanding of the mechanisms underlying infantile epileptic spasms syndrome (IESS). However, over the past decade, significant efforts have been made to develop IESS animal models to provide much‐needed mechanistic information for therapy development.
John W. Swann, Carlos J. Ballester‐Rosado, Chih‐Hong Lee   +2 more
wiley   +1 more source

Circulating Asprosin Declines During 24 Months of Growth Hormone Replacement and Is Associated with IGF-1 and Metabolic Remodeling in Adults with Growth Hormone Deficiency. [PDF]

Int J Mol Sci
Kościuszko M, Buczyńska-Backiel A, Hryniewicka J, Dzięcioł-Anikiej Z, Hernández-Lázaro H, Ceballos-Laita L, Barrio SJD, Adamska A, Siewko K, Zaniuk M, Krętowski AJ, Popławska-Kita A.   +11 more
europepmc   +1 more source

Growth hormone-Insulin-like growth factor 1 axis hyperactivity on bone fibrous dysplasia in McCune-Albright Syndrome. [PDF]

Clin Endocrinol (Oxf), 2018
Tessaris D, Boyce AM, Zacharin M, Matarazzo P, Lala R, De Sanctis L, Collins MT.   +6 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

Progress and Practice of Insulin Resistance in Pregnancy: From Pathogenesis to Management. [PDF]

Int J Med Sci
Zhu Y, Gu H, Li P.
europepmc   +1 more source

Ketogenic diet for infantile epileptic spasms

Epilepsia Open, EarlyView.
Abstract Approximately half of all cases of Infantile Epileptic Spasms Syndrome (IESS) do not respond to vigabatrin and hormonal therapies. There is no clear consensus as to the second‐line therapy for IESS. Ketogenic diet (KD) has emerged as an effective treatment for certain drug‐resistant epilepsies and in many cases of IESS.
Morris H. Scantlebury, Anamika Choudhary, Andy Cheuk‐Him Ng, Cezar Gavrilovici   +3 more
wiley   +1 more source

Precision Dosing for Pediatric Growth Hormone Deficiency With Daily and Weekly Growth Hormone. [PDF]

MedComm (2020)
Wu W, Gong CX, Mei J, Hou L, Liang Y, Ying YQ, Ye F, Ju GH, Tian HX, Yang N, Qin Y, Ouyang D, Luo X.   +12 more
europepmc   +1 more source