Results 251 to 260 of about 203,227 (339)
Modifying Glucose Metabolism Reverses Memory Defects of Alzheimer's Disease Model at Late Stages
Using spatial transcriptomics, we show that ferul enanthate (SL‐ZF‐01) reverses episodic‐like memory deficits in aged, but not young, Alzheimer’s disease (AD) mice. SL restores glucose metabolism and Glucose Transporter 1/3 expression via an ‘Aging‐AD‐Rescue’ pattern, rescuing deficits seen in aged AD mice.
Fang Liu +14 more
wiley +1 more source
Expression of Growth Hormone-Releasing Hormone and Its Receptor Splice Variants in a Cohort of Hungarian Pediatric Patients with Hematological and Oncological Disorders: A Pilot Study. [PDF]
Juhász É +9 more
europepmc +1 more source
CIDEC Restricts Liver Regeneration by Disturbing Lipid Droplet Triglyceride Turnover
This study identifies CIDEC, an lipid droplet (LD)‐fusion associated protein upregulated by CREBH during early regeneration, as a negative regulator of liver regeneration through its unexpected role in sequestering triglyceride (TG) within LDs. CIDEC depletion reduces LD size, mobilizes LD‐stored TG, enhances TG catabolism and free fatty acid (FFA ...
Feng Ouyang +16 more
wiley +1 more source
Effects of Growth Hormone-Releasing Hormone (GHRH) Plasmid Treatment on the Reproductive Productivity of Sows in Primiparous and Multiparous Sow Breeds. [PDF]
Kim MJ +7 more
europepmc +1 more source
This study identifies CARD9 as a key mediator linking sympathetic β2‐adrenergic receptor signaling to macrophage creatine metabolism, inflammatory polarization, and neuronal integrity. Loss of β2‐AR‐PKA‐CREB1‐CARD9 signaling in macrophages reduces creatine uptake, promotes pro‐inflammatory macrophage activation, and drives sympathetic axon ferroptosis.
Huimin Yuan +12 more
wiley +1 more source
Growth hormone-releasing hormone antagonists counteract interferon-γ - induced barrier dysfunction in bovine and human endothelial cells. [PDF]
Fakir S, Barabutis N.
europepmc +1 more source

