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Growth hormone-releasing hormone and cancer
Reviews in Endocrine and Metabolic DisordersThe hypothalamic hormone growth hormone-releasing hormone (GHRH), in addition to promoting the synthesis and release of growth hormone (GH), stimulates the proliferation of human normal and malignant cells by binding to GHRH-receptor (GHRH-R) and its main splice variant, SV1. Both GHRH and GHRH-Rs are expressed in various cancers, forming a stimulatory
Gesmundo, Iacopo +5 more
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Growth hormone-releasing peptide (GHRP)
Cellular and Molecular Life Sciences (CMLS), 1998Growth hormone-releasing peptides and non-peptides (GHRPs. GHRP-GHS) are a new chemical class of GH secretagogues with a chemistry that ranges from small synthetic peptides to peptidomimetics. They release GH in animals and humans by a unique dual and complementary action on the hypothalamus and pituitary.
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Growth hormone- and growth-hormone-releasing hormone-producing tumors
1997Acromegaly, a clinical syndrome of disordered somatic growth and proportion, is usually caused by the unrestrained secretion of growth hormone (GH) by a pituitary adenoma and rarely may result from GH-releasing hormone (GHRH) secretion by an extrapituitary tumor.
I, Shimon, S, Melmed
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Growth hormone‐releasing hormone beyond cancer
Clinical and Experimental Pharmacology and Physiology, 2023Nektarios Barabutis, Saikat Fakir
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Growth Hormone-Releasing Hormone: Clinical Aspects
Journal of Pediatric Endocrinology and Metabolism, 1993B, Moreno Esteban +5 more
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