Results 301 to 310 of about 203,227 (339)

Somatostatin prevents the desensitizing action of growth hormone-releasing factor on growth hormone release

Peptides, 1987
We have investigated the effect of prior exposure to somatostatin (SRIF) alone or in combination with growth hormone-releasing factor (GRF) on the subsequent cyclic AMP and GH responses to GRF in rat anterior pituitary cells in primary culture. The maximal 4.5-fold stimulation of GH release induced by a 3-hr incubation with GRF is reduced by 60 ...
J, Simard, G, Lefèvre, F, Labrie
openaire   +2 more sources

Growth Hormone Releasing Hormone and Growth Hormone Releasing Hormone-Related Peptide in the Testis

1998
Growth hormone releasing hormone (GHRH) is a peptide synthesized in the cell bodies of neurosecretory neurons in the ventromedial and arcuate nuclei of the hypothalamus. When stimulated, GHRH travels down the axons of these neurons and is released into the hypophyseal portal circulation. GHRH binds to receptors on somatotrophs in the anterior pituitary,
K. K. Samaddar, T. M. Todoran, O. Hirsch Pescovitz   +2 more
openaire   +1 more source

Independent effects of growth hormone releasing factor on growth hormone release and gene transcription

Nature, 1985
The synthesis and secretion of growth hormone (GH) by the somatotropic cells of the anterior pituitary is under complex hormonal regulation. The hypothalamic peptides, growth hormone releasing factor (GHRF) and somatostatin, respectively stimulate and block GH release.
M, Barinaga, L M, Bilezikjian, W W, Vale, M G, Rosenfeld, R M, Evans   +4 more
openaire   +2 more sources

Growth Hormone Releasing Hormone

1999
Growth hormone (GH) synthesis and release is regulated by two hypothalamic peptides: somatostatin, which inhibits GH secretion, and growth hormone-releasing hormone (GHRH), which stimulates its release. Although somatostatin was the first to be identified in 1973 (1), the presence of a hypothalamic GH stimulating substance had been predicted in 1960 ...
Paul L. Hofman, O. H. Pescovitz
openaire   +1 more source

The Therapeutic Use of Growth-Hormone-Releasing Hormone

Journal of Pediatric Endocrinology and Metabolism, 1993
As a significant number of children with growth hormone deficiency have been shown to be able to respond to GHRH with a rise in serum growth hormone (GH) levels, GHRH has been used to treat such children with varying success. GHRH has been given subcutaneously (SC) in GH deficient children to improve growth in dose frequencies of daily, twice daily ...
openaire   +3 more sources

Growth hormone- and growth-hormone-releasing hormone-producing tumors

1997
Acromegaly, a clinical syndrome of disordered somatic growth and proportion, is usually caused by the unrestrained secretion of growth hormone (GH) by a pituitary adenoma and rarely may result from GH-releasing hormone (GHRH) secretion by an extrapituitary tumor.
I, Shimon, S, Melmed
openaire   +2 more sources

Growth Hormone-Releasing Hormone: Past and Present

Hormone Research in Paediatrics, 2000
The discovery of hypothalamic hypophysiotropic factors confirmed the hypothesis of Green and Harris in the late 1940s. These hormones were isolated from their eutopic site of production (the hypothalamus) with the exception of growth hormone (GH)-releasing hormone (GHRH), which was isolated from an ectopic, tumoral site of production and found to be ...
openaire   +2 more sources

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

GROWTH-HORMONE RELEASE AND VENEPUNCTURE

The Lancet, 1969
J, Helge, B, Weber, H J, Quabbe
openaire   +2 more sources

Cancer treatment and survivorship statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Kimberly D Miller, Leticia M Nogueira, Angela B Mariotto   +2 more
exaly