Mass Spectrometry-An Alternative in Growth Hormone Measurement [PDF]
Growth hormone (GH) constitutes a set of closely related protein isoforms. In clinical practice, the disagreement of test results between commercially available ligand-binding assays is still an ongoing issue, and incomplete knowledge about the particular function of the different forms leaves an uncertainty of what should be the appropriate measurand.
arxiv +1 more source
Growth-hormone-releasing hormone
Abstract Growth-hormone-releasing hormone (GHRH, somatoliberin) is the hypothalamic peptide hormone that specifically stimulates synthesis and release of growth hormone (GH, somatotropin) by somatotrope cells of the anterior pituitary gland.
openaire +2 more sources
Significance Stem cell therapy is an emerging approach to the treatment of heart failure. Endogenous or transplanted stem cells have limited repair capacity due to damage by exposure to stress.
Victoria Florea+7 more
semanticscholar +1 more source
pS6K1 as an efficacy marker of GnRH agonist with premenopausal breast cancer
Estradiol is a key factor for tumorigenesis and prognosis of hormone receptor-positive breast cancer. Adipocytes are one source of estradiol in patients with breast cancer. Recent studies have shown that phosphorylated ribosomal protein S6 kinase-1 plays
Chan Sub Park+8 more
doaj +1 more source
Comparing adult height gain and menarcheal age between girls with central precocious puberty treated with gonadotropin-releasing hormone agonist alone and those treated with combined growth hormone therapy [PDF]
Purpose This study aimed to investigate the outcomes of gonadotropin-releasing hormone agonist (GnRHa) therapy with or without growth hormone (GH) therapy for girls with idiopathic central precocious puberty (CPP).
Min Sub Kim+4 more
doaj +1 more source
Deprenyl, an old drug with new anticancer potential: Mini review [PDF]
The anticancer potential of monoamine oxidase (MAO) was observed in pre-clinical assays conducted with cell cultures and animals. L-Deprenyl (DEP) causes apoptosis in melanoma, leukemia and mammary cells. High-dose DEP has shown toxicity in mammary and pituitary cancers, as well as in monoblastic leukemia, in rats.
arxiv
Advanced bone age as an indicator facilitates the diagnosis of precocious puberty
Objective: Diagnosis of central precocious puberty has always been challenging in clinical practice. As an important method in the diagnosis of central precocious puberty, luteinizing hormone-releasing hormone stimulation test is complex and time ...
Yue-Qin Xu, Gui-Mei Li, Yan Li
doaj +1 more source
Influence of glucocorticoids on the somatotrophic axis [PDF]
GH secretion is modulated by a complex interplay between two hypothalamic factors, GHRH (growth hormone-releasing hormone) and somatostatin (SRIF). More recently, a third physiological mechanism mediated by GHS (growth hormone secretagogues) and its ...
Correa-Silva, Silvia Regina+1 more
core +3 more sources
Idiopathic combined adrenocorticotropin and growth hormone deficiency mimicking chronic fatigue syndrome [PDF]
A 42-year-old man who had suffered from severe fatigue for 5 years was diagnosed as having chronic fatigue syndrome (CFS) and fibromyalgia. Endocrinological workup using combined anterior pituitary function tests showed that the patient had ...
Ochi, Kanako+2 more
core +1 more source
The Discovery of Growth Hormone‐Releasing Hormone1 [PDF]
This article has been reproduced with permission from the Journal of Clinical Endocrinology & Metabolism.
openaire +5 more sources